{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:20:09Z","timestamp":1787016009170,"version":"build-2736575974"},"reference-count":45,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T00:00:00Z","timestamp":1749081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Research on new\u2010onset hypertensive disorders of pregnancy (HDP) and long\u2010term maternal cardiovascular disease (CVD) death has focused on mothers of small\u2010for\u2010gestational\u2010age infants rather than large\u2010for\u2010gestational\u2010age infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We further explored this focus by investigating CVD death in mothers with HDP by gestational age at delivery across the full spectrum of infant birth size.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We used data from the Medical Birth Registry of Norway, the Norwegian National Population Register, and the Norwegian Cause of Death Registry, with information on mothers giving birth 1967\u20132020. This data was used to predict CVD death in the decades following pregnancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We found the lowest CVD mortality among mothers with no HDP, term delivery, and a first infant with birthweight above average. These women constituted our reference group in the analyses. We found the highest risk of CVD death among mothers with preterm HDP and infants with above average birthweight for gestational age (HR 6.87, 95% CI 4.98, 9.48), not with infants below average birthweight for gestational age (HR 3.06, 95% CI 2.37, 3.93).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There is an interactive association between HDP and large infant birthweight in preterm first births. The high risk associated with the particular combination of HDP, preterm birth, and high infant birthweight for gestational age warrants further research to understand its causal underpinnings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ppe.70033","type":"journal-article","created":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T11:34:01Z","timestamp":1749123241000},"page":"515-523","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Hypertensive Disorders of Pregnancy, Preterm Delivery, and Infant Size: Which Mothers Have Highest Cardiovascular Disease Mortality?"],"prefix":"10.1111","volume":"39","author":[{"given":"Sage","family":"Wyatt","sequence":"first","affiliation":[{"name":"Department of Global Health and Primary Care University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolv","family":"Skj\u00e6rven","sequence":"additional","affiliation":[{"name":"Department of Global Health and Primary Care University of Bergen  Bergen Norway"},{"name":"Center for Fertility and Health Norwegian Institute of Public Health  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Vatten","sequence":"additional","affiliation":[{"name":"Department of Public Health Norwegian University of Science and Technology  Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3376-1311","authenticated-orcid":false,"given":"Allen J.","family":"Wilcox","sequence":"additional","affiliation":[{"name":"Epidemiology Branch National Institute of Environmental Health Sciences  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2302-1723","authenticated-orcid":false,"given":"Aditi","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Global Health and Primary Care University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kari","family":"Klungs\u00f8yr","sequence":"additional","affiliation":[{"name":"Department of Global Health and Primary Care University of Bergen  Bergen Norway"},{"name":"Department of Health Promotion The Norwegian Institute of Public Health  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzan L.","family":"Carmichael","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Stanford University School of Medicine  Stanford California USA"},{"name":"Department of Obstetrics and Gynecology Stanford University School of Medicine  Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils\u2010Halvdan","family":"Morken","sequence":"additional","affiliation":[{"name":"Department of Global Health and Primary Care University of Bergen  Bergen Norway"},{"name":"Department of Obstetrics and Gynecology Haukeland University Hospital  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolv Terje","family":"Lie","sequence":"additional","affiliation":[{"name":"Department of Global Health and Primary Care University of Bergen  Bergen Norway"},{"name":"Center for Fertility and Health Norwegian Institute of Public Health  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6520-9057","authenticated-orcid":false,"given":"Liv Grimstvedt","family":"Kvalvik","sequence":"additional","affiliation":[{"name":"Department of Global Health and Primary Care University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.117.10803"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.036748"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e7677"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2021-055467"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.06.001"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.14522"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.030560"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-99478-4"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)05112-6"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.109.130765"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.004158"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.111.00250"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1586\/14779072.5.2.283"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/FM9.0000000000000125"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2012.01260.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12868"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppe.13064"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppe.12928"},{"key":"e_1_2_8_20_1","unstructured":"\u201cVeileder til Utfylling av Melding til Medisinsk F\u00f8dselsregistrer. Oslo: Nasjonalt Folkehelseinstitutt Avdelig for Helseregistre Divisjon for Epidemiologi \u201d2014."},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2000.079006440.x"},{"key":"e_1_2_8_22_1","unstructured":"World Health Organization \u201cPremature Mortality From Noncommunicable Disease \u201d2024 https:\/\/www.who.int\/data\/gho\/indicator\u2010metadata\u2010registry\/imr\u2010details\/3411."},{"key":"e_1_2_8_23_1","volume-title":"Modern Epidemiology","author":"Rothman K.","year":"2008"},{"key":"e_1_2_8_24_1","unstructured":"World Health Organization \u201cTrends in Maternal Mortality 2000 to 2020: Estimates by WHO UNICEF UNFPA World Bank Group and UNDESA\/Population Division \u201d2023."},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2023.111025"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.16.1720"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwad075"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2006.01.014"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppe.12138"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12159"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.120.14781"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.120.15281"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.117358"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.22107"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38555.462685.8F"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.100248"},{"key":"e_1_2_8_37_1","article-title":"Term Complications and Subsequent Risk of Preterm Birth: Registry Based Study","volume":"369","author":"Kvalvik L. G.","year":"2020","journal-title":"BMJ (Clinical Research Ed.)"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.118.11191"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.03.335"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2021.01.004"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001425"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-010-9527-4"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.831297"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.17454"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyab270"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2022.05.038"}],"container-title":["Paediatric and Perinatal Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ppe.70033","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T06:33:34Z","timestamp":1756362814000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ppe.70033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,5]]},"references-count":45,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1111\/ppe.70033"],"URL":"https:\/\/doi.org\/10.1111\/ppe.70033","archive":["Portico"],"relation":{},"ISSN":["0269-5022","1365-3016"],"issn-type":[{"value":"0269-5022","type":"print"},{"value":"1365-3016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,5]]},"assertion":[{"value":"2024-11-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}