{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T20:31:53Z","timestamp":1785270713495,"version":"3.55.0"},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP\u201067125"],"award-info":[{"award-number":["MOP\u201067125"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT153439"],"award-info":[{"award-number":["PJT153439"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Studies show that foetal and birthweight\u2010for\u2010gestational age centiles are poor predictors of serious neonatal morbidity and neonatal mortality (SNMM) in univariable models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We assessed the predictive performance of multivariable SNMM models based on maternal\/pregnancy characteristics, with and without birthweight centiles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study was based on all live births in the United States, 2019\u20132021, with data obtained from the period live birth\u2010infant death files of the National Center for Health Statistics. SNMM was defined as any one or more of the following: 5\u2010minute Apgar score &lt;\u20094, seizures, assisted ventilation for&gt;\u200930 or neonatal death. SNMM was modelled by log\u2010linear regression on maternal\/pregnancy characteristics as predictors, with and without birthweight centiles. Models were developed for live births at 24\u201342\u2009weeks' and 39\u2009weeks' gestation to all women and those with hypertensive disorders or pre\u2010existing diabetes. Model performance was assessed using area under the curve (AUC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study population included 10,487,243 live births and 221,728 SNMM cases (2.1 per 100 live births). The models with all live births at 24\u201342\u2009weeks' gestation had AUCs of 0.83 (95% confidence interval [CI] 0.82, 0.83) based on maternal\/pregnancy characteristics and 0.83 (95% CI 0.83, 0.84) based on maternal\/pregnancy characteristics and birthweight centiles. However, AUCs of models based on all live births at 39\u2009weeks' gestation were 0.66 (95% CI 0.64, 0.68) with maternal\/pregnancy characteristics and 0.69 (95% CI 0.68, 0.71) with maternal\/pregnancy characteristics and birthweight centiles. AUCs of the models with live births at 39\u2009weeks' gestation to women with pre\u2010existing diabetes were 0.69 (95% CI 0.66, 0.72) based on maternal\/pregnancy characteristics, and 0.77 (95% CI 0.74, 0.79) with the addition of birthweight centiles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Birthweight centiles improve multivariable SNMM predictive performance in specific subpopulations, although evaluation of decision thresholds is required to determine the clinical importance of improvement in predictive ability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ppe.70065","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T07:35:47Z","timestamp":1757403347000},"page":"400-410","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Do Birthweight\u2010For\u2010Gestational Age Centiles Predict Serious Neonatal Morbidity and Neonatal Mortality?"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1119-8772","authenticated-orcid":false,"given":"Sid","family":"John","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology University of British Columbia  Vancouver British Columbia Canada"},{"name":"Children's and Women's Hospital and Health Centre of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. S.","family":"Joseph","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology University of British Columbia  Vancouver British Columbia Canada"},{"name":"Children's and Women's Hospital and Health Centre of British Columbia  Vancouver British Columbia Canada"},{"name":"School of Population and Public Health University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Fahey","sequence":"additional","affiliation":[{"name":"The Reproductive Care Program of Nova Scotia  Halifax Nova Scotia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiliang","family":"Liu","sequence":"additional","affiliation":[{"name":"Centre for Surveillance and Applied Research Public Health Agency of Canada  Ottawa Ontario Canada"},{"name":"School of Epidemiology and Public Health University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarka","family":"Lisonkova","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology University of British Columbia  Vancouver British Columbia Canada"},{"name":"Children's and Women's Hospital and Health Centre of British Columbia  Vancouver British Columbia Canada"},{"name":"School of Population and Public Health University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael S.","family":"Kramer","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Occupational Health McGill University  Montr\u00e9al Quebec Canada"},{"name":"Department of Pediatrics McGill University  Montr\u00e9al Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2006.05.008"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)00522-6"},{"key":"e_1_2_10_4_1","volume-title":"Fetal Growth Restriction (FGR) and Small for Gestational Age (SGA) Newborns","author":"Mandy G. 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