{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:57:15Z","timestamp":1790740635744,"version":"4.1.0"},"reference-count":94,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T00:00:00Z","timestamp":1565568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100011665","name":"Deanship of Scientific Research, King Saud University","doi-asserted-by":"publisher","award":["RG\u20101438\u2010039"],"award-info":[{"award-number":["RG\u20101438\u2010039"]}],"id":[{"id":"10.13039\/501100011665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiologia Plantarum"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:p>We conducted a study to evaluate the interactive effect of NO and H<jats:sub>2<\/jats:sub>S on the cadmium (Cd) tolerance of wheat. Cadmium stress considerably reduced total dry weight, chlorophyll <jats:italic>a<\/jats:italic> and <jats:italic>b<\/jats:italic> content and ratio of Fv\/Fm by 36.7, 48.6, 26.7 and 19.5%, respectively, but significantly enhanced the levels of hydrogen peroxide (H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub>) and malondialdehyde (MDA), endogenous H<jats:sub>2<\/jats:sub>S and NO, and the activities of antioxidant enzymes. Exogenously applied sodium nitroprusside (SNP) and sodium hydrosulfide (NaHS), donors of NO and H<jats:sub>2<\/jats:sub>S, respectively, enhanced total plant dry matter by 47.8 and 39.1%, chlorophyll <jats:italic>a<\/jats:italic> by 92.3 and 61.5%, chlorophyll <jats:italic>b<\/jats:italic> content by 29.1 and 27.2%, Fv\/Fm ratio by 19.7 and 15.2%, respectively, and the activities of antioxidant enzymes, but lowered oxidative stress and proline content in Cd\u2010stressed wheat plants. NaHS and SNP also considerably limited both the uptake and translocation of Cd, thereby improving the levels of some key mineral nutrients in the plants. Enhanced levels of NO and H<jats:sub>2<\/jats:sub>S induced by NaHS were reversed by hypotuarine application, but they were substantially reduced almost to 50% by cPTIO (a NO scavenger) application. Hypotuarine was not effective, but cPTIO was highly effective in reducing the levels of NO and H<jats:sub>2<\/jats:sub>S produced by SNP in the roots of Cd\u2010stressed plants. The results showed that interactive effect of NO and H<jats:sub>2<\/jats:sub>S can considerably improve plant resistance against Cd toxicity by reducing oxidative stress and uptake of Cd in plants as well as by enhancing antioxidative defence system and uptake of some essential mineral nutrients.<\/jats:p>","DOI":"10.1111\/ppl.13012","type":"journal-article","created":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T14:59:44Z","timestamp":1564066784000},"page":"345-360","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":266,"title":["Responses of nitric oxide and hydrogen sulfide in regulating oxidative defence system in wheat plants grown under cadmium stress"],"prefix":"10.1111","volume":"168","author":[{"given":"Cengiz","family":"Kaya","sequence":"first","affiliation":[{"name":"Soil Science and Plant Nutrition Department Harran University  Sanliurfa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Ashraf","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biology and Biotechnology, The University of Lahore  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Nasser","family":"Alyemeni","sequence":"additional","affiliation":[{"name":"Botany and Microbiology Department College of Science, King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2734-4180","authenticated-orcid":false,"given":"Parvaiz","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Botany and Microbiology Department College of Science, King Saud University  Riyadh Saudi Arabia"},{"name":"Department of Botany S.P. 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