{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T12:22:59Z","timestamp":1791462179553,"version":"4.3.4"},"reference-count":60,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T00:00:00Z","timestamp":1676419200000},"content-version":"vor","delay-in-days":45,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["KYZZ2022001"],"award-info":[{"award-number":["KYZZ2022001"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiologia Plantarum"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The plant parasitic nematode <jats:italic>Aphelenchoides besseyi<\/jats:italic> is a major pest that poses serious threats to different vegetables and crop plants. In the present study, volatiles isolated from <jats:italic>Bacillus<\/jats:italic> spp. were utilized as green biocontrol agents to overcome nematodes. In in vitro experiment, <jats:italic>Bacillus<\/jats:italic> spp. GBSC56, SYST2, and FZB42 showed the strongest nematicidal activity with killing rates of 80.78%, 75.69%, and 60.45%, respectively, as compared with control. The selected synthetic volatile organic compounds (VOCs), namely albuterol, benzaldehyde (BDH), 1,2\u2010benzisothiazol\u20103(2H)\u2010one (1,2\u2010HIT), dimethyl disulfide (DMDS), 2\u2010undecanone (2\u2010UD), and 1,3\u2010propanediole (1,3\u2010PD), exhibited strong nematicidal activity, with <jats:italic>A. besseyi<\/jats:italic> killing rate of 85.58%, 82.65%, 81.75%, 80.36%, 84.45%, and 82.36%, respectively, at 400\u2009\u03bcg\/mL. Microscopic analysis proved that the rapid mortality was due to the production of reactive oxygen species (ROS). Molecular docking attributed this ROS production to the nematicidal effect of synthetic VOCs on NADH DEHYDROGENASE SUBUNIT 2, which is known to play a critical role in the suppression of ROS in nematode models. In a greenhouse experiment, the <jats:italic>Bacillus<\/jats:italic> strains GBSC56, SYST2, and FZB42 and their synthetic VOCs significantly improved the physiological parameters in terms of growth promotion traits. In addition, selected genes related to growth promotion and defense genes showed a significant upregulation of their expression in rice seedlings treated with those synthetic VOCs. Overall, these findings revealed that the selected <jats:italic>Bacillus<\/jats:italic> strains and their synthetic VOCs possess high potential against <jats:italic>A. besseyi<\/jats:italic>. Moreover, this study also sheds new light on the mechanisms by which specific <jats:italic>Bacillus<\/jats:italic> nematicidal VOCs influence important genes involved in rice plant growth promotion and could effectively be used to suppress plant parasitic nematodes.<\/jats:p>","DOI":"10.1111\/ppl.13868","type":"journal-article","created":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T17:33:50Z","timestamp":1675272830000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["High killing rate of nematode and promotion of rice growth by synthetic volatiles from <i>Bacillus<\/i> strains due to enhanced oxidative stress response"],"prefix":"10.1111","volume":"175","author":[{"given":"Qurban","family":"Ali","sequence":"first","affiliation":[{"name":"Key Laboratory of Integrated Management of Crop Diseases and Pests, Department of Plant Pathology, College of Plant Protection Nanjing Agricultural University  Nanjing 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