{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:50:51Z","timestamp":1790355051067,"version":"4.1.0"},"reference-count":95,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T00:00:00Z","timestamp":1725235200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["23\u201014\u201000327"],"award-info":[{"award-number":["23\u201014\u201000327"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiologia Plantarum"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Lichens are important components of high\u2010latitude boreal and Arctic habitats. While stress tolerant, they are among the most sensitive ecosystem components to climate change, in particular, an increase in ultraviolet light (UV) arising from polar ozone depletion and deforestation. This study is the first to explore the effects of UV\u2010B on gene expression in lichens to predict metabolic pathways involved in tolerance. Using transcriptome profiling and bioinformatic analyses, here we studied the effects of UV\u2010B on gene expression in lichens using <jats:italic>Lobaria pulmonaria<\/jats:italic> (L.) Hoff. as a model species. UV\u2010B exposure causes significant browning of the upper cortex of the thallus, which correlates to an increased expression of biosynthetic gene clusters involved in the synthesis of eu\u2010 and allomelanins and melanin precursors. Based on transcriptome analyses, we suggest that the biosynthesis of melanins and other secondary metabolites, such as naphthalene derivates, tropolones, anthraquinones, and xanthones, is a trade\u2010off that lichens pay to protect essential metabolic processes such as photosynthesis and respiration. Expression profiles of general stress\u2010associated genes, in particular, related to reactive oxygen species scavenging, protection of proteins, and DNA repair, clearly indicate that the mycobiont is the more UV\u2010B\u2010responsive and susceptible partner in lichen symbiosis. Our findings demonstrate that UV\u2010B stress activates an intricate gene network involved in tolerance mechanisms of lichen symbionts. Knowledge obtained here may enable the prediction of likely effects on lichen biodiversity caused by climate change and pollution.<\/jats:p>","DOI":"10.1111\/ppl.14512","type":"journal-article","created":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T09:31:24Z","timestamp":1725269484000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Ultraviolet\u2010induced melanisation in lichens: physiological traits and transcriptome profile"],"prefix":"10.1111","volume":"176","author":[{"given":"Ilya","family":"Leksin","sequence":"first","affiliation":[{"name":"Kazan Institute of Biochemistry and Biophysics, FRC Kazan Scientific Center, Russian Academy of Sciences  Kazan Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikhail","family":"Shelyakin","sequence":"additional","affiliation":[{"name":"Institute of Biology of Komi Science Centre of the Ural Branch of the Russian Academy of Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilya","family":"Zakhozhiy","sequence":"additional","affiliation":[{"name":"Institute of Biology of Komi Science Centre of the Ural Branch of the Russian Academy of Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Kozlova","sequence":"additional","affiliation":[{"name":"Kazan (Volga Region) Federal University  Kazan Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0530-4244","authenticated-orcid":false,"given":"Richard","family":"Beckett","sequence":"additional","affiliation":[{"name":"Kazan Institute of Biochemistry and Biophysics, FRC Kazan Scientific Center, Russian Academy of Sciences  Kazan Russian Federation"},{"name":"University of KwaZulu\u2010Natal  Scottsville South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0827-181X","authenticated-orcid":false,"given":"Farida","family":"Minibayeva","sequence":"additional","affiliation":[{"name":"Kazan Institute of Biochemistry and Biophysics, FRC Kazan Scientific Center, Russian Academy of Sciences  Kazan Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.16814"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jksus.2010.06.022"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu638"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/sysbio\/syr041"},{"key":"e_1_2_9_6_1","volume-title":"Executive Summary. Scientific Assessment of Ozone Depletion: 2022","author":"Anonymous","year":"2022"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envexpbot.2021.104655"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0024282911000387"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)43948-3"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2018.06.004"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-25001-4_29"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43630-023-00371-y"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkad344"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu170"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-10-421"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11103-016-0468-5"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msab293"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms13055768"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp348"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.16281"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-014-3809-y"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02187-09"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-32215-1"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13199-016-0468-x"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof8080791"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/plants11030295"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.funeco.2017.01.005"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004420000541"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2018.10.021"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2016.03.014"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.3389\/ffunb.2021.777474"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btab007"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/250158"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2010.08.016"},{"key":"e_1_2_9_35_1","first-page":"175","volume-title":"Lichen metabolites: an overview of some secondary metabolites and their biological potential","author":"Goga M.","year":"2020"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8SC05126G"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.623839"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/sysbio\/syq010"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dci.2018.11.007"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2012.09.003"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-56359-1_9"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu031"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-14-870"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbx108"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-42637-0"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3317"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01111-21"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erq376"},{"key":"e_1_2_9_49_1","article-title":"Fast gene set enrichment analysis","volume":"060012","author":"Korotkevich G.","year":"2021","journal-title":"BioRxiv"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/icb\/45.5.734"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab301"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.simyco.2016.02.001"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.1905.05051"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/gbe\/evad002"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.12.10.1939"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fbr.2018.10.002"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0024282916000293"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0024282906005706"},{"key":"e_1_2_9_59_1","first-page":"143","article-title":"Solar radiation screening in usnic acid\u2010containing cortices of the lichen Nephroma arcticum","volume":"43","author":"McEvoy M.","year":"2007","journal-title":"Symbiosis"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.3732\/ajb.91.3.449"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mst024"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3054.1988.tb09176.x"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm321"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.00223-22"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03263124"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1039\/c3np70064j"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msu300"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10886-007-9339-5"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00442-004-1583-6"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0093371"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.18520\/cs\/v119\/i2\/176-185"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/29.9.e45"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1093\/gbe\/evaa189"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.funbio.2015.02.005"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1134\/S0006297920050119"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23102617"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp616"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1039\/c8pp00526e"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1093\/oso\/9780198542919.003.0008"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1080\/15592324.2016.1256530"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04364-9"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/217037"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119143611.ch5"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11738-022-03457-9"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.17516\/1997-1389-0359"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1134\/S1021443721060182"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-22746-2_11"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-8137.2003.00708.x"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1890\/EHS15-0008R1.1"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2018.08.033"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40694-022-00138-7"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1875-5364(18)30050-5"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.csbj.2021.11.033"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2017.03.013"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.17816\/ecogen15605"},{"key":"e_1_2_9_96_1","doi-asserted-by":"publisher","DOI":"10.2174\/092986707782023253"}],"container-title":["Physiologia Plantarum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ppl.14512","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T00:08:28Z","timestamp":1741738108000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ppl.14512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":95,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1111\/ppl.14512"],"URL":"https:\/\/doi.org\/10.1111\/ppl.14512","archive":["Portico"],"relation":{},"ISSN":["0031-9317","1399-3054"],"issn-type":[{"value":"0031-9317","type":"print"},{"value":"1399-3054","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"2024-05-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14512"}}