{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:58:37Z","timestamp":1791230317116,"version":"4.1.0"},"reference-count":81,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,2,16]],"date-time":"2025-02-16T00:00:00Z","timestamp":1739664000000},"content-version":"vor","delay-in-days":46,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002383","name":"King Saud University","doi-asserted-by":"publisher","award":["RSP2025R154"],"award-info":[{"award-number":["RSP2025R154"]}],"id":[{"id":"10.13039\/501100002383","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiologia Plantarum"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Global crop productivity is consistently threatened by cadmium (Cd) soil contamination. Crosstalk between nitric oxide (NO) and melatonin (MT) in enhancing crop resilience to heavy metal stress has gained significant attention. Here, we evaluated the joint effect of sodium nitroprusside (SNP; 200\u2009\u03bcM as NO donor) and MT (100\u2009\u03bcM) on Cd\u2010stressed eggplant (\n                    <jats:italic>Solanum melongena<\/jats:italic>\n                    L.). Cd stress significantly reduced plant growth, biomass yield, leaf pigments, and biochemical properties. Conversely, SNP, MT, and particularly their combined (SNP\u2009+\u2009MT) application reduced Cd toxicity and enhanced growth and physio\u2010biochemical traits of eggplants. For instance, at 50\u2009mg Cd kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    soil, SNP, MT, and SNP\u2009+\u2009MT increased root biomass (41.6, 30, and 47%), total chlorophyll (30.7, 26.3, and 46%), soluble protein (20.5, 17.6 and 37%) and RLWC (23, 17.5, and 29%) over their respective control. Furthermore, SNP\u2009+\u2009MT significantly (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009\u2264\u20090.05) reduced levels of EL, H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    , proline, and MDA by 54.5, 66, 61 and 70%, respectively, in Cd\u2010stressed eggplants. SNP\u2009+\u2009MT interplay enhanced antioxidant defense responses in leaf tissues under Cd stress. Besides, SNP and MT upregulated transcript levels of\n                    <jats:italic>POD<\/jats:italic>\n                    ,\n                    <jats:italic>SOD<\/jats:italic>\n                    ,\n                    <jats:italic>CAT<\/jats:italic>\n                    , and\n                    <jats:italic>GPX<\/jats:italic>\n                    genes in eggplants under Cd stress. SNP and MT applications improved essential nutrient cation homeostasis in Cd\u2010stressed shoot tissues of eggplants. Moreover, SNP\u2009+\u2009MT lessens metal\u2010induced toxicity by decreasing Cd uptake, translocation (TF) and bioconcentration (BCF) factors. Conclusively, these findings validated the beneficial defensive interaction between SNP and MT in regulating Cd tolerance in eggplants. However, further research is needed to uncover the underlying defensive mechanisms of these synergistic effects.\n                  <\/jats:p>","DOI":"10.1111\/ppl.70130","type":"journal-article","created":{"date-parts":[[2025,2,16]],"date-time":"2025-02-16T23:10:46Z","timestamp":1739747446000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["<scp>NO<\/scp>\n                    and melatonin interplay augment Cd\u2010tolerance mechanism in eggplants:\n                    <scp>ROS<\/scp>\n                    detoxification and regulation of gene expression"],"prefix":"10.1111","volume":"177","author":[{"given":"Waquar Akhter","family":"Ansari","sequence":"first","affiliation":[{"name":"Marwadi University Research Center, Dept. of Agriculture, Faculty of Science Marwadi University  Rajkot Gujarat 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