{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:10:30Z","timestamp":1791832230329,"version":"4.3.4"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T00:00:00Z","timestamp":1772928000000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiologia Plantarum"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Auxin plays a central role in shaping root system architecture (RSA) by regulating cell division, differentiation, primary root elongation, and lateral root (LR) initiation and emergence. Iron (Fe) is an essential micronutrient required for photosynthesis, chlorophyll biosynthesis, and redox metabolism. Fe availability has a significant impact on plant health, development, and yield. Here, we investigate the role of the auxin biosynthetic gene TRYPTOPHAN AMINOTRANSFERASE RELATED2 (\n                    <jats:italic>TAR2<\/jats:italic>\n                    ) in coordinating LR development and Fe homeostasis in\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Arabidopsis thaliana<\/jats:italic>\n                    <\/jats:styled-content>\n                    . Fe deficiency increased auxin accumulation in roots, as observed through\n                    <jats:italic>DR5rev:GFP<\/jats:italic>\n                    reporter activity, and this response required\n                    <jats:italic>TAR2<\/jats:italic>\n                    function to drive Fe deficiency\u2010induced modifications to RSA. The\n                    <jats:italic>tar2\u20101<\/jats:italic>\n                    mutant displayed significantly reduced visible LR numbers, total LR length and LR density. Yeast one\u2010hybrid assays identified several Fe deficiency\u2010responsive bHLH transcription factors, including\n                    <jats:italic>bHLH34<\/jats:italic>\n                    ,\n                    <jats:italic>bHLH38<\/jats:italic>\n                    ,\n                    <jats:italic>bHLH39<\/jats:italic>\n                    , and\n                    <jats:italic>PYE<\/jats:italic>\n                    , that directly bind the\n                    <jats:italic>TAR2<\/jats:italic>\n                    promoter, indicating a regulatory link between Fe signaling and auxin biosynthesis. Together, our findings support that\n                    <jats:italic>TAR2<\/jats:italic>\n                    \u2010dependent local auxin biosynthesis is a major contributor to LR development and the adaptive reprogramming of RSA in response to Fe deficiency.\n                  <\/jats:p>","DOI":"10.1111\/ppl.70828","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T06:57:15Z","timestamp":1773039435000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Iron Deficiency Reprograms Lateral Root Growth via\n                    <scp>\n                      <i>TAR2<\/i>\n                    <\/scp>\n                    \u2010Dependent Auxin Biosynthesis in\n                    <scp>\n                      <i>Arabidopsis<\/i>\n                    <\/scp>"],"prefix":"10.1111","volume":"178","author":[{"given":"Budha Ratna","family":"Rav","sequence":"first","affiliation":[{"name":"Department of Biological Sciences Indian Institute of Science Education and Research, (IISER) Mohali  SAS Nagar Punjab India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2770-656X","authenticated-orcid":false,"given":"Santosh B.","family":"Satbhai","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences Indian Institute of Science Education and Research, (IISER) Mohali  SAS Nagar Punjab India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4020-2686-7_22"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365313X.2008.03421.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.13.4.843"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0036210"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/pcp\/pcu039"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.110.161109"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.104.024315"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1153795"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.119.1.71"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20101\u20104939\u20107003\u20102_13"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.111.092973"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.arplant.59.032607.092949"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/ert080"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.2.11.1071"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.086363"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0099234"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erp232"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2013.09.039"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/17800"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.4161\/psb.1.6.3511"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.202014"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/mp\/ssr104"}],"container-title":["Physiologia Plantarum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ppl.70828","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ppl.70828","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ppl.70828","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T01:53:38Z","timestamp":1777686818000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ppl.70828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1111\/ppl.70828"],"URL":"https:\/\/doi.org\/10.1111\/ppl.70828","archive":["Portico"],"relation":{},"ISSN":["0031-9317","1399-3054"],"issn-type":[{"value":"0031-9317","type":"print"},{"value":"1399-3054","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2025-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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