{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T09:13:33Z","timestamp":1788426813806,"version":"build-2803163510"},"reference-count":54,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"vor","delay-in-days":37,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiologia Plantarum"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Selenium (Se), a beneficial element, plays a pivotal role in mitigating plant stress, yet its potential in alleviating manganese (Mn) toxicity in apple trees remains poorly understood. This study explores the potential of Se in alleviating Mn\u2010induced stress in\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Malus domestica<\/jats:italic>\n                    <\/jats:styled-content>\n                    Borkh. cv. Red Fuji, a cultivar known for its sensitivity to Mn. Through a combination of physiological analysis and transcriptomic profiling, we provide comprehensive insights into the mechanisms by which Se enhances Mn tolerance. The results demonstrated that selenite application balanced nutrient elements, stabilized the photosynthetic system, and reduced oxidative stress. Additionally, selenite promoted cell wall remodeling and modulated hormone levels. Transcriptome analysis further revealed that selenite regulated genes associated with polyunsaturated fatty acid hydrolase, sucrose hydrolase, and photosynthesis, indicating its role in alleviating Mn stress. GO and KEGG enrichment analyses highlighted that differentially expressed genes were enriched in pathways related to phenylpropanoid biosynthesis, alpha\u2010linolenic acid metabolism, and galactose metabolism, suggesting key metabolic pathways involved in Mn stress responses. Weighted gene co\u2010expression network analysis (WGCNA) identified core module genes strongly correlated with antioxidant enzymes and substances, chlorophyll content, and mineral element concentrations. In conclusion, Se effectively mitigates Mn stress in \u2018Fuji\u2019 apples through multi\u2010level regulatory mechanisms, providing a theoretical foundation for the application of Se\u2010enriched agriculture in apple cultivation.\n                  <\/jats:p>","DOI":"10.1111\/ppl.71054","type":"journal-article","created":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T07:24:42Z","timestamp":1786087482000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Selenium Alleviates Manganese Toxicity in \u2018Red Fuji\u2019 Apple: Insights From Combined Physiological and Transcriptomic Approaches"],"prefix":"10.1111","volume":"178","author":[{"given":"Wanying","family":"Xie","sequence":"first","affiliation":[{"name":"School of Horticulture Ludong University  Yantai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixing","family":"Wei","sequence":"additional","affiliation":[{"name":"Dongying 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