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However, research on the underlying mechanisms of cold resistance remains relatively scarce in blue honeysuckle. Here, we demonstrate that the\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>L. caerulea<\/jats:italic>\n                    <\/jats:styled-content>\n                    transcription factors LcNAC72 interacts with LcDREB1, as revealed by yeast two\u2010hybrid co\u2010immunoprecipitation, luciferase complementation Imaging, and bimolecular fluorescence complementation assays.\n                    <jats:italic>Agrobacterium<\/jats:italic>\n                    \u2010mediated transient overexpression showed that\n                    <jats:italic>LcNAC72<\/jats:italic>\n                    \u2010\n                    <jats:italic>LcDREB1<\/jats:italic>\n                    cooperatively modulate reactive oxygen species homeostasis to preserve cellular integrity under low temperature. Transgenic plants overexpressing LcNAC72 exhibited markedly attenuated membrane lipid peroxidation and enhanced antioxidant enzyme activity, whereas silenced plants showed exacerbated oxidative damage. Comparative transcriptomic analysis of LcNAC72\u2010overexpressing Arabidopsis under low temperature further demonstrated significant alteration of MAPK cascade\u2010related genes, suggesting a potential association of the LcNAC72\u2010LcDREB1 module with MAPK\u2010mediated signaling during cold responses. These findings provide a solid basis for exploring the genetic and molecular underpinnings of low\u2010temperature adaptation in\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>L. caerulea<\/jats:italic>\n                    <\/jats:styled-content>\n                    .\n                  <\/jats:p>","DOI":"10.1111\/ppl.71075","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T10:58:23Z","timestamp":1787050703000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>\n                      <i>LcNAC72<\/i>\n                    <\/scp>\n                    \u2010\n                    <scp>\n                      <i>LcDREB1<\/i>\n                    <\/scp>\n                    Regulatory Module Mediates Low\u2010Temperature Stress Response by Enhancing\n                    <scp>ROS<\/scp>\n                    Scavenging Capacity in\n                    <scp>\n                      <i>Lonicera caerulea<\/i>\n                    <\/scp>"],"prefix":"10.1111","volume":"178","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9958-1700","authenticated-orcid":false,"given":"Dandan","family":"Zang","sequence":"first","affiliation":[{"name":"Key Laboratory of Edible Wild Vegetables (NFGA) Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences  Harbin China"},{"name":"Huma Cold Temperature Plant Germplasm Resources Protection Field Scientific Observation and Research Station of Heilongjiang Province Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences  Huma China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0128-1599","authenticated-orcid":false,"given":"Yadong","family":"Duan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Edible Wild Vegetables (NFGA) Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences  Harbin China"},{"name":"Huma Cold Temperature Plant Germplasm Resources Protection Field Scientific Observation and Research Station of Heilongjiang Province Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences  Huma China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huizi","family":"Liu","sequence":"additional","affiliation":[{"name":"Zhejiang Institute of Subtropical Crops Zhejiang Academy of Agricultural Sciences  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3851-4202","authenticated-orcid":false,"given":"Yiming","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Life Sciences Qilu Normal University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengfeng","family":"Li","sequence":"additional","affiliation":[{"name":"Food Processing Research Institute Heilongjiang Academy of Agricultural 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