{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T03:06:41Z","timestamp":1791860801612,"version":"4.3.4"},"reference-count":51,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T00:00:00Z","timestamp":1787443200000},"content-version":"vor","delay-in-days":53,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiologia Plantarum"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Phenylpropanoids are specialized metabolites involved in multiple aspects of plant physiology and contribute to fruit quality and human health benefits. In sweet cherry (\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Prunus avium<\/jats:italic>\n                    <\/jats:styled-content>\n                    L.), metabolomic studies have largely focused on fruits, showing that cultivar identity contributes to phenylpropanoid pathway specialization. However, the contribution of genotype to phenylpropanoid organization in other organs, particularly leaves, remains poorly understood. Here, we applied an untargeted metabolomics approach to investigate genotype\u2010associated phenylpropanoid pathway specialization in sweet cherry leaves, using fruits as a reference organ. Leaves and fruits from seven sweet cherry cultivars (\u201cEarly Bigi\u201d, \u201cBurlat\u201d, \u201cSandra\u201d, \u201cGrace Star\u201d, \u201cRomana\u201d, \u201cDurone Rosso\u201d, and \u201cFerrovia\u201d), representing early\u2010, mid\u2010 and late\u2010ripening genotypes, were sampled at full fruit maturity across multiple orchards and over two consecutive growing seasons. Distinct organ\u2010specific phenylpropanoid profiles were observed, with fruits characterized by the accumulation of anthocyanins, flavan\u20103\u2010ols, and simple hydroxycinnamic acids, and leaves enriched in flavonols, hydroxycinnamic acids, and structurally diverse phenylpropanoid derivatives. Multivariate and univariate analyses identified cultivar identity as a major component of phenylpropanoid pathway specialization within each organ. Genotype\u2010associated differences involved multiple phenylpropanoid subclasses and remained detectable across growing seasons and orchard locations. Overall, these findings indicate differential channeling of the phenylpropanoid pathway between fruits and leaves and show that, within the range of environmental conditions covered by the present experimental design, genotype\u2010associated variation contributes to shaping phenylpropanoid composition in sweet cherry leaves, revealing a level of organization that had not been previously established in this organ.\n                  <\/jats:p>","DOI":"10.1111\/ppl.71083","type":"journal-article","created":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T23:55:47Z","timestamp":1787529347000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Genotype\u2010Dependent Phenylpropanoid Pathway Specialization in\n                    <i>Prunus avium<\/i>\n                    Fruits and Leaves Revealed by Untargeted Metabolomics"],"prefix":"10.1111","volume":"178","author":[{"given":"Giuseppe","family":"Ardagna","sequence":"first","affiliation":[{"name":"Department of Biotechnology University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Gambini","sequence":"additional","affiliation":[{"name":"Department of Biotechnology University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Bulgarini","sequence":"additional","affiliation":[{"name":"Department of Biotechnology University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Negri","sequence":"additional","affiliation":[{"name":"Department of Biotechnology University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martino","family":"Bianconi","sequence":"additional","affiliation":[{"name":"Department of Biotechnology University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia","family":"Di Carlo","sequence":"additional","affiliation":[{"name":"Department of Biological, Chemical and Pharmaceutical Sciences and Technologies University of Palermo  Palermo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Ceoldo","sequence":"additional","affiliation":[{"name":"Department of Biotechnology University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia","family":"Guzzo","sequence":"additional","affiliation":[{"name":"Department of Biotechnology University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6474-8577","authenticated-orcid":false,"given":"Mauro","family":"Commisso","sequence":"additional","affiliation":[{"name":"Department of Biotechnology University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,23]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plantsci.2012.07.014"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scienta.2006.03.014"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox9080677"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15030681"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41438-020-00445-3"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tifs.2019.02.052"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/plants12010103"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/pca.2549"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.4c02146"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/11263504.2021.1897705"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lwt.2023.115085"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/nutraceuticals5020012"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0180889"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.8106"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00217-018-3055-y"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00217-018-3198-x"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.134223"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00299-025-03645-0"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erae048"},{"key":"e_1_2_12_21_1","doi-asserted-by":"crossref","unstructured":"Gerasko T. 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