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Interindividual variability in the response to microbial triggers in the sulcus plays an important role in the onset and progression of periodontal diseases. Host genetic variants can influence this variability, affecting the response of the host to the subgingival biofilm. Genetic factors affecting tooth eruption could potentially influence susceptibility to periodontal diseases and, specifically, susceptibility to localized aggressive periodontitis. This review aims to discuss the evidence available for the role of host genetic variants in tooth eruption and to and to give some directions for prospective research in this topic.<\/jats:p>","DOI":"10.1111\/prd.12158","type":"journal-article","created":{"date-parts":[[2017,11,30]],"date-time":"2017-11-30T05:56:39Z","timestamp":1512021399000},"page":"35-42","source":"Crossref","is-referenced-by-count":7,"title":["Development of the gingival sulcus at the time of tooth eruption and the influence of genetic 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