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Therapeutic intervention includes introduction of techniques to change behavior, such as: individually tailored oral\u2010hygiene instructions; a smoking\u2010cessation program; dietary adjustment; subgingival instrumentation to remove plaque and calculus; local and systemic pharmacotherapy; and various types of surgery. No single treatment option has shown superiority, and virtually all types of mechanical periodontal treatment benefit from adjunctive antimicrobial chemotherapy. 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