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Periodontitis is defined by pathologic loss of the periodontal ligament and alveolar bone. The disease involves complex dynamic interactions among active herpesviruses, specific bacterial pathogens and destructive immune responses. Periodontal diagnostics is currently based on clinical rather than etiologic criteria, and provides limited therapeutic guidance. Periodontal causative treatment consists of scaling, antiseptic rinses and occasionally systemic antibiotics, and surgical intervention has been de\u2010emphasized, except perhaps for the most advanced types of periodontitis. Plastic surgical therapy includes soft\u2010tissue grafting to cover exposed root surfaces and bone grafting to provide support for implants. Dental implants are used to replace severely diseased or missing teeth, but implant overuse is of concern. The utility of laser treatment for periodontitis remains unresolved. Host modulation and risk\u2010factor modification therapies may benefit select patient groups. Patient self\u2010care is a critical part of periodontal health care, and twice\u2010weekly oral rinsing with 0.10\u20100.25% sodium hypochlorite constitutes a valuable adjunct to conventional anti\u2010plaque and anti\u2010gingivitis treatments. A link between periodontal herpesviruses and systemic diseases is a strong biological plausibility. In summary, research during the past 25\u00a0years has significantly changed our concepts of periodontitis pathobiology and has produced more\u2010effective and less\u2010costly therapeutic options.\n                  <\/jats:p>","DOI":"10.1111\/prd.12221","type":"journal-article","created":{"date-parts":[[2017,7,31]],"date-time":"2017-07-31T03:25:33Z","timestamp":1501471533000},"page":"7-23","source":"Crossref","is-referenced-by-count":1043,"title":["Periodontitis: facts, fallacies and the future"],"prefix":"10.1111","volume":"75","author":[{"given":"J\u00f8rgen","family":"Slots","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,31]]},"reference":[{"key":"e_1_2_14_2_1","first-page":"190","article-title":"Effect of sodium hypochlorite solution on the subgingival microflora of juvenile periodontitis lesions","volume":"5","author":"Adcock JE","year":"1983","journal-title":"Pediatr 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