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Morbidity and mortality can be completely different among these diseases, with outcome being dependent on an early and accurate diagnosis, systemic comorbidities, and the patient's response to treatment. Definitive diagnosis is based on clinical and histopathologic findings. Because clinical presentations among these diseases are often similar, different immunofluorescence tests and <jats:styled-content style=\"fixed-case\">ELISAs<\/jats:styled-content> are used to confirm the specific diagnosis. Oral mucosa may often be the first site of clinical manifestation from which the disease spreads to other mucosal surfaces and skin. Thus, often dentists and oral medicine specialists may be the first to encounter patients with such diseases. In this review we discuss the most frequent autoimmune vesicobullous disorders, namely pemphigus vulgaris, mucous membrane pemphigoid, bullous pemphigoid, and linear IgA disease.<\/jats:p>","DOI":"10.1111\/prd.12263","type":"journal-article","created":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T07:50:54Z","timestamp":1557906654000},"page":"77-88","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Oral autoimmune vesicobullous diseases: Classification, clinical presentations, molecular mechanisms, diagnostic algorithms, and management"],"prefix":"10.1111","volume":"80","author":[{"given":"Stefania","family":"Leuci","sequence":"first","affiliation":[{"name":"Oral Medicine Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences Federico II University of Naples  Naples 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