{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T20:58:47Z","timestamp":1793134727464,"version":"4.5.0"},"reference-count":153,"publisher":"Wiley","license":[{"start":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T00:00:00Z","timestamp":1700697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Periodontology 2000"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. \u201cCardiovascular Diseases (CVDs).\u201d WHO, February 1, 2017,<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/cardiovascular-diseases-\">https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/cardiovascular\u2010diseases\u2010<\/jats:ext-link>(cvds)). Cardiovascular diseases are a group of disorders affecting the heart and blood vessels. They encompass a collection of different conditions, among which atherosclerotic cardiovascular disease (ASCVD) is the most prevalent. CVDs caused by atherosclerosis, that is, ASCVD, are particularly fatal: with heart attack and stroke being together the most prevalent cause of death in the world. To reduce the health burden represented by ASCVD, it is urgent to identify the nature of the \u201cresidual risk,\u201d beyond the established risk factors (e.g., hypertension) and behavioral factors already maximally targeted by drugs and public health campaigns. Remarkably, periodontitis is increasingly recognized as an independent cardiovascular risk factor.<\/jats:p>","DOI":"10.1111\/prd.12528","type":"journal-article","created":{"date-parts":[[2023,11,25]],"date-time":"2023-11-25T00:59:39Z","timestamp":1700873979000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Periodontitis and atherosclerotic cardiovascular disease: A\u00a0critical appraisal"],"prefix":"10.1111","author":[{"given":"Maria Clotilde","family":"Carra","sequence":"first","affiliation":[{"name":"UFR d'Odontologie Universit\u00e9 Paris Cit\u00e9 Paris France"},{"name":"Service of Odontology, Periodontal and Oral Surgery Unit Rothschild Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris (AP\u2010HP) Paris France"},{"name":"INSERM\u2010 Sorbonne Paris Cit\u00e9 Epidemiology and Statistics Research Centre (CRESS) Paris 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