{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T05:22:23Z","timestamp":1787721743744,"version":"build-2784847793"},"reference-count":125,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Periodontology 2000"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To provide a concise overview of the biological events and dimensional changes following tooth extraction and to summarize current therapeutic strategies for extraction site management, including alveolar ridge preservation (ARP), alveolar ridge reconstruction (ARR), partial extraction therapies (PET), and tooth autotransplantation (TAT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>This narrative review summarizes the biological mechanisms underlying post\u2010extraction healing and evaluates evidence\u2010based approaches for extraction site management. Clinical decision\u2010making is discussed according to hard and soft tissue integrity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Tooth extraction initiates a physiological remodeling process that frequently results in alveolar ridge resorption, potentially compromising subsequent prosthetic rehabilitation. To minimize post\u2010extraction changes and establish a favorable biological foundation for tooth replacement, treatment should be tailored to site\u2010specific characteristics. ARP is generally effective in limiting dimensional changes in sockets with intact alveolar walls, whereas ARR aims to restore ridge architecture in sites with substantial hard tissue defects, such as buccal dehiscences. PET and TAT are also viable alternatives for preserving alveolar ridge dimensions in selected cases. When indicated, immediate implant placement combined with interceptive therapies, including ARP, ARR, or PET, represents a feasible approach to shorten total treatment time. Careful clinical and radiographic assessment is essential to make sound decisions in commonly encountered clinical scenarios: (1) intact hard and soft tissues; (2) damaged alveolar bone without soft tissue dehiscence; and (3) combined hard and soft tissue deficiencies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ARP, ARR, PET, and TAT are predictable, evidence\u2010based treatment modalities for the management of extraction sites. Optimal treatment planning should be based on site\u2010specific characteristics and patient\u2010related factors to maximize clinical outcomes and minimize postoperative complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/prd.70074","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T05:01:42Z","timestamp":1787720502000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Management of extraction sites: From biological principles to clinical practice"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9989-4483","authenticated-orcid":false,"given":"Emilio","family":"Couso\u2010Queiruga","sequence":"first","affiliation":[{"name":"Department of Oral Surgery and Stomatology University of Bern School of Dental Medicine  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo","family":"Avila\u2010Ortiz","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dental Medicine  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,25]]},"reference":[{"issue":"6","key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1902\/jop.2008.070551","article-title":"Strategic extraction: a paradigm shift that is changing our profession","volume":"79","author":"Kao RT","year":"2008","journal-title":"J Periodontol"},{"issue":"11","key":"e_1_2_11_3_1","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1034\/j.1600-051x.2000.027011824.x","article-title":"Initial extractions and tooth loss during supportive care in a periodontal population seeking comprehensive care","volume":"27","author":"Tonetti 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