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Subsequently, progression to dementia with <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>ewy bodies was suspected based on neuropsychological and neuroimaging findings; additionally, one of the three patients suffered from visual hallucinations. Neuropsychological examinations such as subjective contours, cube copying and block design in the <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>echsler <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>dult <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ntelligence <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cale\u2010<jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> revealed visuoperceptual dysfunction in all three patients even when other cognitive functions were rather preserved. Brain magnetic resonance imaging revealed no significant brain atrophy, including in the parieto\u2010occipital area and the hippocampus, while brain <jats:sup>18<\/jats:sup><jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>\u2010fluorodeoxyglucose positron emission tomography demonstrated right dominant metabolic reductions in the occipital lobe, including the primary visual cortex, in all three patients. We suggest the possibility of progression to dementia with <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>ewy bodies, but not <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> or posterior cortical atrophy. Regardless of the presence of core features and prodromal non\u2010motor symptoms, this progression is suggested when there are difficulties only in higher\u2010level visual processing such as subjective contours and block design in the <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>echsler <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>dult <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ntelligence <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cale\u2010<jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>, no significant atrophy of the parieto\u2010occipital area and hippocampus on brain magnetic resonance imaging, and hypometabolism in the occipital lobe including the primary visual cortex on brain <jats:sup>18<\/jats:sup><jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>\u2010fluorodeoxyglucose positron emission tomography.<\/jats:p>","DOI":"10.1111\/psyg.12039","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T11:37:05Z","timestamp":1392637025000},"page":"72-80","source":"Crossref","is-referenced-by-count":3,"title":["Three presenile patients in which neuropsychological and neuroimaging examinations suggest possible progression to dementia with <scp>L<\/scp>ewy bodies"],"prefix":"10.1111","volume":"14","author":[{"given":"Kazumi","family":"Ota","sequence":"first","affiliation":[{"name":"PET\/CT Dementia Research Center Juntendo Tokyo Koto Geriatric Medical Center Juntendo University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eizo","family":"Iseki","sequence":"additional","affiliation":[{"name":"PET\/CT Dementia Research Center Juntendo Tokyo Koto Geriatric Medical Center Juntendo University School of Medicine  Tokyo Japan"},{"name":"Department of Psychiatry Juntendo University School of Medicine  Tokyo 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