{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:56:37Z","timestamp":1778633797999,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,7,13]],"date-time":"2016-07-13T00:00:00Z","timestamp":1468368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Japanese Ministry of Education, Culture, Science, and Technology"},{"name":"Japanese Ministry of Labour, Health and Welfare"},{"DOI":"10.13039\/501100008919","name":"Kidani Memorial Trust Cancer Treatment Project","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100008919","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychogeriatrics"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Cognitive decline is common among older adults with cancer. The present study aimed to investigate the impact of cognitive decline on health utility value in older adults suffering from cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients aged 65\u2009years or older with a primary diagnosis of malignant lymphoma or multiple myeloma were recruited. Patients were asked to complete the <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>uro<jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content>\u20105 (<jats:styled-content style=\"fixed-case\">EQ\u20105D<\/jats:styled-content>) scale to measure health utility and the <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ini\u2010<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ental <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tate <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>xamination to assess cognitive decline. The potential impact of cognitive decline was investigated with univariate analysis. A multivariate regression analysis was conducted to control for potential confounding factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Complete data were obtained from 87 patients, 29% of whom had cognitive decline. The mean\u2009\u00b1\u2009SE <jats:styled-content style=\"fixed-case\">EQ\u20105D<\/jats:styled-content> score for patients with cognitive decline was significantly lower than that for those without cognitive decline (0.67\u2009\u00b1\u20090.04 vs 0.79\u2009\u00b1\u20090.03, <jats:italic>t<\/jats:italic>\u2009=\u20092.38, <jats:italic>P<\/jats:italic>\u2009=\u20090.02). However, multiple regression analysis showed that cognitive decline was not significantly associated with <jats:styled-content style=\"fixed-case\">EQ\u20105D<\/jats:styled-content> scores. Female sex and lower performance scores (worse physical condition) were significantly associated with <jats:styled-content style=\"fixed-case\">EQ\u20105D<\/jats:styled-content> scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Cognitive decline may be involved in decreased health utility value in older adult patients with cancer. However, this effect does not seem to be independent, and the patient's physical condition may be a relevant confounding factor.<\/jats:p><\/jats:sec>","DOI":"10.1111\/psyg.12205","type":"journal-article","created":{"date-parts":[[2016,7,14]],"date-time":"2016-07-14T05:43:03Z","timestamp":1468474983000},"page":"149-154","source":"Crossref","is-referenced-by-count":7,"title":["Does cognitive decline decrease health utility value in older adult patients with cancer?"],"prefix":"10.1111","volume":"17","author":[{"given":"Tatsuo","family":"Akechi","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Cognitive\u2010Behavioral Medicine Nagoya City University Graduate School of Medical Sciences  Nagoya Japan"},{"name":"Division of Palliative Care and Psycho\u2010oncology Nagoya City University Hospital  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayo","family":"Aiki","sequence":"additional","affiliation":[{"name":"Department of Psychiatry 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