{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:34:35Z","timestamp":1761766475466,"version":"3.40.5"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,2,7]],"date-time":"2019-02-07T00:00:00Z","timestamp":1549497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004733","name":"Universidade de Macau","doi-asserted-by":"publisher","award":["MYRG2015\u201000230\u2010FHS","MYRG2016\u201000005\u2010FHS"],"award-info":[{"award-number":["MYRG2015\u201000230\u2010FHS","MYRG2016\u201000005\u2010FHS"]}],"id":[{"id":"10.13039\/501100004733","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psychogeriatrics"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Depressive disorders are common in old age. Antipsychotics (APs) are often used as an adjunctive treatment with antidepressants (ADs) in this population but its patterns of use in Asia are not known. This study explored the rate of combination of APs and ADs in older adult psychiatric patients in Asia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a secondary analysis of the database of a multicentre study which recorded participants\u2019 basic demographical and clinical data in standardised format in 10 Asian countries and territories. The data were analysed using univariate and multivariate logistic regression analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 955 older adult psychiatric in\u2010 and outpatients were included in this study. The proportion of concurrent AP and AD use was 32.0%, ranging from 23.3% in Korea to 44.0% in Taiwan. Multivariate logistic regression analysis found that younger age, inpatient status and diagnosis of schizophrenia, anxiety and other mental disorders were significantly related to a higher proportion of concurrent use of APs and ADs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Around a third of older adult psychiatric patients had concurrent AP and AD use in the Asian countries\/regions surveyed. Considering the uncertain effectiveness and questionable safety of the AP and AD combination in this patient population, such should be cautiously used.<\/jats:p><\/jats:sec>","DOI":"10.1111\/psyg.12416","type":"journal-article","created":{"date-parts":[[2019,2,8]],"date-time":"2019-02-08T01:45:16Z","timestamp":1549590316000},"page":"333-339","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Concurrent antipsychotic use in older adults treated with antidepressants in Asia"],"prefix":"10.1111","volume":"19","author":[{"given":"Min","family":"Dong","sequence":"first","affiliation":[{"name":"Unit of Psychiatry, Faculty of Health Sciences University of Macau  Macao SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang\u2010Nan","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery The Affiliated Hospital of Southwest Medical University  Luzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinge","family":"Zhang","sequence":"additional","affiliation":[{"name":"The National Clinical Research Center for Mental Disorders, China &amp; Center of Depression, Beijing Institute for Brain Disorders &amp; Mood Disorders Center, Beijing Anding Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabor S.","family":"Ungvari","sequence":"additional","affiliation":[{"name":"University of Notre Dame Australia  Fremantle Australia"},{"name":"Division of Psychiatry School Medicine, University of Western Australia  Perth Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chee H.","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen F. 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