{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T14:00:37Z","timestamp":1784383237779,"version":"3.55.0"},"reference-count":53,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T00:00:00Z","timestamp":1581033600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Taoyuan Psychiatric Center, Ministry of Health and Welfare of Taiwan","award":["TYPC-201401"],"award-info":[{"award-number":["TYPC-201401"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psychogeriatrics"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>It has been emphasised that benzodiazepines and related drugs (BZDRs) should be used cautiously in people with dementia. The aim of this study was to identify factors associated with inappropriate prescription patterns of BZDRs including polypharmacy, long\u2010term treatment and high doses among patients with dementia taking BZDRs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective chart review study of patients with dementia who were treated at the study hospital. The date that the patient was issued a catastrophic illness certificate from the National Health Insurance Administration was used as the index date. Medical records of the 2\u2010year period after the index date were reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 308 patients with dementia were included in this study. Among them, 151 (49.0%) received at least one prescription of BZDRs. After adjusting for covariates, psychiatric comorbidities (adjusted odds ratio (aOR) = 4.74, 95% CI = 1.75\u201312.81), history of past suicidal behaviour (aOR = 4.25, 95% CI = 1.40\u201312.88) and long\u2010term treatment with BZDRs (aOR = 3.38, 95% CI = 1.11\u201310.27) were associated with polypharmacy of BZDRs. Age (aOR = 1.05, 95% CI = 1.0\u20131.11) and polypharmacy (aOR = 3.57, 95% CI = 1.23\u201310.32) were associated with long\u2010term treatment. Living with family (aOR = 3.33, 95% CI = 1.32\u20139.79) and fewer psychiatric admissions to the study hospital (aOR = 0.56, 95% CI = 0.36\u20130.86) were associated with treatment with high doses of BZDRs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Treatment with BZDRs is prevalent in patients with dementia. Inappropriate prescription patterns of BZDRs are not uncommon in these patients and may be interlinked.<\/jats:p><\/jats:sec>","DOI":"10.1111\/psyg.12527","type":"journal-article","created":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T20:49:40Z","timestamp":1581108580000},"page":"447-457","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The factors associated with inappropriate prescription patterns of benzodiazepines and related drugs among patients with dementia"],"prefix":"10.1111","volume":"20","author":[{"given":"Shin\u2010Chiao","family":"Tien","sequence":"first","affiliation":[{"name":"Department of Psychiatry Taoyuan Psychiatric Centre  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8479-5418","authenticated-orcid":false,"given":"Hung\u2010Yu","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Taoyuan Psychiatric Centre  Taoyuan Taiwan"},{"name":"Department of Psychiatry National Taiwan University Hospital and School of Medicine, National Taiwan University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun\u2010Chi","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Taoyuan Psychiatric Centre  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-64012-3.00002-2"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2016.09.010"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-199040020-00008"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h369"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/hup.745"},{"key":"e_1_2_9_7_1","first-page":"5","article-title":"Other D, Rabins PV, et al. 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