{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T04:08:49Z","timestamp":1791864529051,"version":"4.3.4"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T00:00:00Z","timestamp":1588636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psychogeriatrics"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Day services (DS) are part of the public nursing care system in Japan. The purpose of DS is to help elderly individuals maintain mental and physical functions, eliminate feelings of isolation among homebound users, and reduce the burden of care on family members. However, the relationship between DS and the progression of Alzheimer's disease (AD) remains unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed 161 AD patients based on available Mini\u2010Mental State Examination (MMSE) scores. The patients were divided into two groups: those who started to use DS (<jats:italic>n<\/jats:italic> = 106) and those who did not use DS (<jats:italic>n<\/jats:italic> = 55). We then compared the groups\u2019 MMSE scores between the first memory clinic visit and the 6\u2010month point.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no significant differences between the two groups with regard to sex and the number of family members, but the non\u2010DS group was younger, had more education, and had better MMSE scores at the first visit. At 6\u2009months, we found a significant improvement in the MMSE scores of DS users, reflecting improved cognitive function. In addition, lower MMSE score at the first visit was associated with greater improvement in MMSE score at 6\u2009months. Interestingly, the frequency of DS use had no significant effect on MMSE score. However, after approximately 6\u2009months, DS use significantly improved the cognitive function of AD patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>DS use significantly improved the cognitive function of AD patients. However, most DS users in Japan are older and have severe dementia. Patients who are younger, have more education, or have mild dementia dislike using DS. As a significant difference was found in the MMSE scores between the two groups after 6\u2009months, DS use appears to be a useful non\u2010drug therapy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/psyg.12558","type":"journal-article","created":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T04:03:52Z","timestamp":1588737832000},"page":"620-624","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Use of day services improved cognitive function in patients with Alzheimer's disease"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8756-6714","authenticated-orcid":false,"given":"Yasuyuki","family":"Honjo","sequence":"first","affiliation":[{"name":"Department of Memory Clinic Kyoto Miniren Asukai Hospital  Kyoto Japan"},{"name":"Department of Memory Clinic Biwako\u2010Yoikuin Hospital  Otsu Japan"},{"name":"Department of Memory Clinic Kyoto\u2010Kaisei Hospital  Kyoto Japan"},{"name":"Department of Memory Clinic Seika National Insurance Hospital  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuki","family":"Ide","sequence":"additional","affiliation":[{"name":"Uehiro Research Division for iPS Cell Ethics, Center for iPS Cell Research and Application (CiRA) Kyoto University  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Takechi","sequence":"additional","affiliation":[{"name":"Department of Geriatrics and Cognitive Disorders Fujita Health University School of Medicine  Toyoake Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,5]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"77","article-title":"Education for community\u2010based family medicine: a social need in the real world","volume":"60","author":"Taniguchi SI","year":"2017","journal-title":"Acta Med 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