{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T11:50:19Z","timestamp":1788868219800,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,8,19]],"date-time":"2020-08-19T00:00:00Z","timestamp":1597795200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["(no. 19dk0207037h0003)"],"award-info":[{"award-number":["(no. 19dk0207037h0003)"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psychogeriatrics"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>People living with early\u2010onset dementia (EOD) have specific social needs. Epidemiological studies are needed to obtain current information and provide appropriate service planning. This study aimed to clarify the current prevalence and subtype distribution of EOD, as well as the services frequently used by individuals with EOD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A multisite, population\u2010based, two\u2010step study was conducted. Questionnaires were sent to 26\u2009416 candidate facilities in 12 areas with a target population of 11\u2009630\u2009322 to inquire whether any individuals with EOD had sought services or stayed during the last 12\u2009months (step 1). When \u201cyes\u201d responses were received, additional questionnaires were sent to the facilities both to complete and to distribute to the target individuals with EOD to obtain more detailed information, including the dementia subtype (step 2).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In step 1, valid responses were obtained from 16\u2009848 facilities (63.8%), and 4077 cases were identified. In step 2, detailed information was obtained for 1614 cases (39.6%) from the facilities and 530 cases (13.0%) from the individuals. The national EOD prevalence rate was estimated to be 50.9\/100\u2009000 population at risk (95% confidence interval: 43.9\u201357.9; age range, 18\u201364\u2009years). The number of individuals with EOD was estimated to be 35\u2009700 as of 2018. Alzheimer\u2010type dementia (52.6%) was the most frequent subtype, followed by vascular dementia (17.1%), frontotemporal dementia (9.4%), dementia due to traumatic brain injury (4.2%), dementia with Lewy bodies\/Parkinson's disease dementia (4.1%), and dementia due to alcohol\u2010related disorders (2.8%). Individuals with EOD were most frequently identified at medical centers for dementia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The prevalence rate estimated in this study was comparable to those in previous studies in Japan. However, the subtype distribution differed, with Alzheimer\u2010type dementia being the most prominent. Based on the case identification frequencies, medical centers for dementia are expected to continue to function as the primary special health service by providing quality diagnosis and post\u2010diagnostic support for individuals with EOD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/psyg.12596","type":"journal-article","created":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T10:02:01Z","timestamp":1598608921000},"page":"817-823","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Prevalence and subtype distribution of early\u2010onset dementia in Japan"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6861-6977","authenticated-orcid":false,"given":"Shuichi","family":"Awata","sequence":"first","affiliation":[{"name":"Research Team for Promoting Independence and Mental Health Tokyo Metropolitan Institute of Gerontology  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayako","family":"Edahiro","sequence":"additional","affiliation":[{"name":"Research Team for Promoting Independence and Mental Health Tokyo Metropolitan Institute of Gerontology  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuaki","family":"Arai","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Division of Clinical Medicine University of Tsukuba  Tsukuba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manabu","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Osaka University Graduate School of Medicine  Suita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Ikeuchi","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics, Brain Research Institute Niigata University  Niigata Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinobu","family":"Kawakatsu","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry, Aizu Medical Center Fukushima Medical University  Aizu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoko","family":"Konagaya","sequence":"additional","affiliation":[{"name":"Division of Research Obu Dementia Care and Training Center  Obu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuo","family":"Miyanaga","sequence":"additional","affiliation":[{"name":"Yukiguni\u2010Yamato Hospital  Niigata Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidetaka","family":"Ota","sequence":"additional","affiliation":[{"name":"Advanced Research Center for Geriatric and Gerontology Akita University  Akita 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