{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T17:38:46Z","timestamp":1787593126582,"version":"build-2736575974"},"reference-count":81,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T00:00:00Z","timestamp":1752451200000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psychogeriatrics"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This review evaluates the role of vitamins in neurodegeneration. Low levels of B vitamins have been associated with cognitive decline. B vitamins may help inhibit amyloid plaque aggregation. Vitamin D deficiency has been linked to an increased risk of cognitive impairment, correlating with Alzheimer's pathology. Vitamin E may help delay Alzheimer's disease progression and support functional abilities. In Parkinson's disease, vitamin D shows promise in reducing dopaminergic neuron loss and improving motor and cognitive outcomes. Vitamin C reduces oxidative stress and preserves neuronal integrity. Vitamin K has gained attention for its role in cognitive health, with studies suggesting that higher levels may be linked to improved cognitive performance. In conclusion, a better understanding of the translational potential of these vitamins may inform preventive and therapeutic strategies for neurodegenerative diseases. Clinicians should consider vitamin supplementation for aging\u2010related conditions. Further studies are needed to confirm its therapeutic potential and clarify underlying mechanisms in neurodegeneration.<\/jats:p>","DOI":"10.1111\/psyg.70071","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T23:25:35Z","timestamp":1752535535000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Role of Vitamins in Neurodegeneration: A Brief Review of Mechanisms, Clinical Evidence, and\u00a0Therapeutic Perspectives"],"prefix":"10.1111","volume":"25","author":[{"given":"Alberto","family":"Raggi","sequence":"first","affiliation":[{"name":"Unit of Neurology G.B. Morgagni \u2013 L. 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