{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:41:36Z","timestamp":1790257296396,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100007132","name":"Otsuka Pharmaceutical","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007132","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psychogeriatrics"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Previous studies of community\u2010dwelling people with Alzheimer's disease (AD) have reported an association between the severe neuropsychiatric symptoms (NPS) of dementia and caregiver burden. We explored the current status of family caregiver burden, NPS of dementia, and care service usage in Japanese community\u2010dwelling people with AD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A web\u2010based questionnaire was administered to cohabitant family caregivers of community\u2010dwelling people with AD from 13 to 27 November 2023. Amongst 8108 participants registered in the panel data, 705 family caregivers (age: 19\u201379\u2009years) were selected. Participants completed the Japanese version of the Neuropsychiatric Inventory\u2010Brief Questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Family caregivers (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009705) had a mean\u2009\u00b1\u2009standard deviation (SD) age of 54.6\u2009\u00b1\u200911.5\u2009years, 56.9% were male, and 84.0% cared for a parent or in\u2010law with AD. Patients with AD had a mean\u2009\u00b1\u2009SD age of 84.2\u2009\u00b1\u20098.8\u2009years; 26.2% were male, and 90.6% had NPS, including 73.4% with hyperactivity (agitation, disinhibition, irritability and aberrant motor behaviour). Mean\u2009\u00b1\u2009SD caregiving time per week was higher for caregivers of patients with NPS versus without NPS (24.1\u2009\u00b1\u200922.1 vs. 17.6\u2009\u00b1\u200914.0\u2009h). The dissatisfaction with nursing care support services was higher amongst caregivers of patients with NPS vs. without NPS. To manage hyperactivity, 11.3% of caregivers administered medication and 11.5% relocated patients to a calm environment; 16.6% of the caregivers had no way to cope. Amongst caregivers who responded \u2018administer medication\u2019 in response to hyperactivity, 32.1% had care staff or a medical provider come in and administer oral medication and 18.9% took the patient to a medical facility to receive an injection or intravenous treatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Caregiving for AD patients with NPS (vs. without NPS) was associated with longer duration of caregiving, greater usage of nursing care services and dissatisfaction with nursing care support services.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/psyg.70143","type":"journal-article","created":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T03:58:22Z","timestamp":1771041502000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Family Caregiver Burden and Neuropsychiatric Symptoms in Japanese Community\u2010Dwelling People With Alzheimer's Disease: A Cross\u2010Sectional Study Using\u00a0a Web\u2010Based Questionnaire"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8731-9887","authenticated-orcid":false,"given":"Tomoyuki","family":"Nagata","sequence":"first","affiliation":[{"name":"Center for Dementia\u2010Related Diseases Airanomori Hospital  Kagoshima Japan"},{"name":"Department of Psychiatry The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5952-6141","authenticated-orcid":false,"given":"Shunichiro","family":"Shinagawa","sequence":"additional","affiliation":[{"name":"Department of Psychiatry The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6952-7770","authenticated-orcid":false,"given":"Shinichi","family":"Noto","sequence":"additional","affiliation":[{"name":"Faculty of Rehabilitation Science Niigata University of Health and Welfare  Niigata Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5027-6289","authenticated-orcid":false,"given":"Kentaro","family":"Yamato","sequence":"additional","affiliation":[{"name":"Medical Affairs Otsuka Pharmaceutical Co., Ltd.  Tokyo Japan"},{"name":"Department of Public Health, Graduate School of Medicine Juntendo University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9948-5260","authenticated-orcid":false,"given":"Naoki","family":"Mori","sequence":"additional","affiliation":[{"name":"Medical Affairs Otsuka Pharmaceutical Co., Ltd.  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6395-5275","authenticated-orcid":false,"given":"Keisuke","family":"Onuki","sequence":"additional","affiliation":[{"name":"Medical Affairs Otsuka Pharmaceutical Co., Ltd.  Tokyo Japan"},{"name":"Department of Public Health, Graduate School of Medicine Juntendo University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,13]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.114.148403"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-019-1260-3"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2014.12.018"},{"key":"e_1_2_11_5_1","first-page":"278","article-title":"BPSD of Alzheimer's Disease and Factors That Affect Care Burden","volume":"25","author":"Nukariya K.","year":"2013","journal-title":"Japanese Journal of General Hospital 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