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The present study used videos of biologically prepared, conditioned stimuli (tarantulas) to test the efficacy of delayed extinction in blocking reconsolidation of conditioned fear in healthy young adults. Strong differential conditioning, measured by skin conductance, was observed among a screened subset of participants during acquisition. However, the delayed\u2010extinction intervention failed to reduce reactivity to the conditioned stimulus paired with the extinction delay. These results are partially consistent with other recent, mixed findings and point to a need for testing other candidate interventions designed to interfere with the reconsolidation process.<\/jats:p>","DOI":"10.1111\/psyp.12687","type":"journal-article","created":{"date-parts":[[2016,6,17]],"date-time":"2016-06-17T13:40:06Z","timestamp":1466170806000},"page":"1343-1351","source":"Crossref","is-referenced-by-count":18,"title":["Delayed extinction fails to reduce skin conductance reactivity to fear\u2010conditioned stimuli"],"prefix":"10.1111","volume":"53","author":[{"given":"Jon","family":"Fricchione","sequence":"first","affiliation":[{"name":"Department of Psychiatry Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark S.","family":"Greenberg","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin","family":"Spring","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nellie","family":"Wood","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Mueller\u2010Pfeiffer","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy University Hospital Zurich, University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed R.","family":"Milad","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger K.","family":"Pitman","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott P.","family":"Orr","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,6,17]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1223006"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2012.5"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7652558"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.2012.01384.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1037\/\/0278-6133.19.suppl1.57"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1037\/\/0033-2909.125.2.171"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2004.08.018"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.psych.55.090902.142050"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.2971-04.2004"},{"key":"e_1_2_5_11_1","first-page":"1","volume-title":"Methods in psychophysiology","author":"Edelberg R.","year":"1967"},{"key":"e_1_2_5_12_1","first-page":"132","volume-title":"SCID\u20101 Clinician Version","author":"First M. 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