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Clinically stable adult inpatients (<jats:italic>N<\/jats:italic>\u00a0=\u00a0157) and matched community participants (<jats:italic>N<\/jats:italic>\u00a0=\u00a090) participated in a standard auditory sensory gating protocol. Responses to paired clicks were quantified as peak\u2010to\u2010peak amplitude from a response at approximately 50\u00a0ms to a response at approximately 100\u00a0ms in MEG\u2010derived source waveforms. For bilateral sources in each of four regions near Heschl's gyrus, the gating ratio was computed as the response to the second stimulus divided by the response to the first stimulus. Spectrally resolved Granger causality quantified effective connectivity among regions manifested in alpha\u2010band oscillatory coupling before and during stimulation. Poorer sensory gating localized to A1 in SZ than in controls confirmed previous results, here found in adjacent brain regions as well. Spontaneous, stimulus\u2010independent effective connectivity within the hemisphere from angular gyrus to portions of the superior temporal gyrus was lower in SZ and correlated with gating ratio. Significant involvement of frontal and subcortical brain regions previously proposed as contributing to the auditory gating abnormality was not found. Findings point to endogenous connectivity evident in a sequence of activity from angular gyrus to portions of superior temporal gyrus as a mechanism contributing to normal and abnormal gating in SZ and potentially to sensory and cognitive symptoms.<\/jats:p>","DOI":"10.1111\/psyp.13770","type":"journal-article","created":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T07:46:50Z","timestamp":1611560810000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Oscillatory connectivity as a mechanism of auditory sensory gating and its disruption in schizophrenia"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5495-1376","authenticated-orcid":false,"given":"Tzvetan","family":"Popov","sequence":"first","affiliation":[{"name":"Methods of Plasticity Research Laboratory Department of Psychology University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Rockstroh","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Konstanz  Konstanz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory A.","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Psychology UCLA  Los Angeles CA USA"},{"name":"Department of Psychiatry and Biobehavioral Sciences UCLA  Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,24]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"Ackenheil M. 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