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Beneficial effects of taVNS have been demonstrated on symptoms in patients with mental or neurological disorders as well as transdiagnostic dimensions, including mood and motivation. However, since taVNS research is still an emerging field, the underlying neurophysiological processes are not yet fully understood, and the replicability of findings on biomarkers of taVNS effects has been questioned. The objective of this analysis was to synthesize the current evidence concerning the effects of taVNS on vagally mediated heart rate variability (vmHRV), a candidate biomarker that has, so far, received most attention in the field. We performed a living Bayesian random effects meta\u2010analysis. To keep the synthesis of evidence transparent and up to date as new studies are being published, we developed a Shiny web app that regularly incorporates new results and enables users to modify study selection criteria to evaluate the robustness of the inference across potential confounds. Our analysis focuses on 16 single\u2010blind studies comparing taVNS versus sham in healthy participants. The meta\u2010analysis provides strong evidence for the null hypothesis (\n                    <jats:italic>g<\/jats:italic>\n                    \u00a0=\u00a00.014, CI\n                    <jats:sub>shortest<\/jats:sub>\n                    = [\u22120.103, 0.132], BF\n                    <jats:sub>01<\/jats:sub>\n                    = 24.678), indicating that acute taVNS does not alter vmHRV compared to sham. To conclude, there is no support for the hypothesis that vmHRV is a robust biomarker for acute taVNS. By increasing transparency and timeliness, the concept of living meta\u2010analyses can lead to transformational benefits in emerging fields such as non\u2010invasive brain stimulation.\n                  <\/jats:p>","DOI":"10.1111\/psyp.13933","type":"journal-article","created":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T14:23:22Z","timestamp":1630592602000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":106,"title":["Does transcutaneous auricular vagus nerve stimulation affect vagally mediated heart rate variability? A living and interactive Bayesian meta\u2010analysis"],"prefix":"10.1111","volume":"58","author":[{"given":"Vinzent","family":"Wolf","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Psychotherapy, T\u00fcbingen Center for Mental Health (T\u00fcCMH) University of T\u00fcbingen T\u00fcbingen Germany"},{"name":"Department of Psychology University of Salzburg Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3066-3801","authenticated-orcid":false,"given":"Anne","family":"K\u00fchnel","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy, T\u00fcbingen Center for Mental Health (T\u00fcCMH) University of T\u00fcbingen T\u00fcbingen Germany"},{"name":"Department of Translational Research in Psychiatry Max Planck Institute of Psychiatry and International Max Planck Research School for Translational Psychiatry (IMPRS\u2010TP) Munich 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