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Recent studies of event\u2010related potentials (ERPs) suggest that robust congruency sequence effects (CSEs)\u2014a popular index of adaptive control\u2014appear in confound\u2010minimized designs. Thus, the present study sought to determine whether a confound\u2010minimized CSE paradigm could identify adaptive control dysfunction in people with major depressive disorder (MDD), generalized anxiety disorder (GAD), and obsessive\u2010compulsive disorder (OCD). We predicted that participants with MDD and GAD would show smaller ERP CSEs and that participants with OCD would show larger ERP CSEs than healthy controls. Data from 44 people with GAD, 51 people with MDD, 31 people with OCD, and 56 healthy comparison participants revealed normal CSEs as indexed by response times (RTs) and ERPs in the psychopathology groups. Moreover, psychiatric symptoms did not moderate these CSEs. Finally, we observed a strong mean\u2013variance relationship in RT CSEs, such that participants with stronger post\u2010recruitment of control in mean RT scores showed the most consistent post\u2010conflict responses (i.e., the least intraindividual variability). These findings suggest that prior findings from confound\u2010laden tasks indicating altered CSEs in psychopathology stem from processes that are unrelated to adaptive control. Future research should employ experimental designs that isolate these processes to advance our understanding of abnormal CSEs in psychopathology.<\/jats:p>","DOI":"10.1111\/psyp.14426","type":"journal-article","created":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T07:14:17Z","timestamp":1693898057000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Normal congruency sequence effects in psychopathology: A behavioral and electrophysiological examination using a confound\u2010minimized design"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4437-6598","authenticated-orcid":false,"given":"Peter E.","family":"Clayson","sequence":"first","affiliation":[{"name":"Department of Psychology University of South Florida  Tampa Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John L.","family":"Shuford","sequence":"additional","affiliation":[{"name":"Department of Psychology University of South Florida  Tampa Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Rast","sequence":"additional","affiliation":[{"name":"Department of Psychology University of California \u2013 Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott A.","family":"Baldwin","sequence":"additional","affiliation":[{"name":"Department of Psychology Brigham Young University  Provo Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel H.","family":"Weissman","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8199-8065","authenticated-orcid":false,"given":"Michael J.","family":"Larson","sequence":"additional","affiliation":[{"name":"Department of Psychology Brigham Young University  Provo Utah USA"},{"name":"Neuroscience Center Brigham Young University  Provo Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0012589"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-44462000000300003"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924\u20109338(97)86748\u2010X"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0035628"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.12401"},{"key":"e_1_2_6_7_1","volume-title":"Beck Depression Inventory\u2014Second Edition (BDI\u2010II)","author":"Beck A. 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