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This condition may make it possible to test whether sensorimotor deprivation alters specific dimensions of empathic reactivity to observed pain. To explore this issue, we asked SCI people with paraplegia and healthy controls to observe videos of painful or neutral stimuli administered to a hand (intact) or a foot (deafferented). The stimuli were displayed by means of a virtual reality set\u2010up and seen from a first person (1PP) or third person (3PP) visual perspective. A number of measures were recorded ranging from explicit behaviors like explicit verbal reports on the videos, to implicit measures of muscular activity (like EMG from the corrugator and zygomatic muscles that may represent a proxy of sensorimotor empathy) and of autonomic reactivity (like the electrodermal response and Respiratory Sinus Arrhythmia that may represent a general proxy of affective empathy). While no across group differences in explicit verbal reports about the pain stimuli were found, SCI people exhibited reduced facial muscle reactivity to the stimuli applied to the foot (but not the hand) seen from the 1PP. Tellingly, the corrugator activity correlated with SCI participants' neuropathic pain. There were no across group differences in autonomic reactivity suggesting that SCI lesions may affect sensorimotor dimensions connected to empathy for pain.<\/jats:p>","DOI":"10.1111\/psyp.14547","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T11:39:03Z","timestamp":1708342743000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Topographic mapping of the sensorimotor qualities of empathic reactivity: A psychophysiological study in people with spinal cord injuries"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0853-8975","authenticated-orcid":false,"given":"Michele","family":"Scandola","sequence":"first","affiliation":[{"name":"NPSY.Lab\u2010VR, Department of Human Sciences University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0728-3045","authenticated-orcid":false,"given":"Maddalena","family":"Beccherle","sequence":"additional","affiliation":[{"name":"NPSY.Lab\u2010VR, Department of Human Sciences University of Verona  Verona Italy"},{"name":"CLN<sup>2<\/sup>S@Sapienza, Istituto Italiano di Tecnologia, Department of Psychology Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5812-3762","authenticated-orcid":false,"given":"Rossella","family":"Togni","sequence":"additional","affiliation":[{"name":"\u201cG. 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