{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T16:50:56Z","timestamp":1782406256381,"version":"3.54.5"},"reference-count":74,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:00:00Z","timestamp":1781654400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32200909"],"award-info":[{"award-number":["32200909"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psychophysiology"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Inhibitory control is frequently impaired under anxiety, yet the temporal dynamics through which oxytocin (OXT) modulates this process remain poorly understood. This randomized, double\u2010blind, placebo\u2010controlled pharmacological event\u2010related potential (ERP) study investigated how intranasal OXT (24 IU) influences neural and behavioral correlates of inhibitory control under threat\u2010of\u2010shock (anxiety) and safe conditions in 100 healthy male university students. Participants performed an interference\u2010inhibition working memory task requiring attention to either emotional faces (social) or house scenes (non\u2010social) while ignoring superimposed task\u2010irrelevant stimuli. ERPs across distinct processing stages (N1, P2, N2, N450) were analyzed. OXT did not significantly affect behavioral performance. However, it produced stage\u2010specific, context\u2010dependent neuromodulatory effects. Specifically, OXT (1) modulated early perceptual processing of social stimuli under anxiety, as indicated by a reduced P2 amplitude to faces; (2) influenced conflict\u2010monitoring, as reflected by an anxiety\u2010dependent attenuation of the N2 response during the non\u2010social task; and (3) modulated later conflict resolution processes, evidenced by a double dissociation in the N450 component: OXT prevented the anxiety\u2010induced increase in N450 for houses while enhancing the N450 response to faces under threat. This study provides temporal insights into the neurophysiological effects of OXT, indicating that OXT modulates inhibitory control through multi\u2010stage neural processes rather than a general anxiolytic effect.<\/jats:p>","DOI":"10.1111\/psyp.70342","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T07:29:25Z","timestamp":1781681365000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Oxytocin Modulates Inhibitory Control via Neural\u2010Temporal Mechanisms"],"prefix":"10.1111","volume":"63","author":[{"given":"Wei","family":"Yi","sequence":"first","affiliation":[{"name":"School of Psychology Shenzhen University  Shenzhen China"},{"name":"Shenzhen Key Laboratory of Affective and Social Cognitive Science Shenzhen University  Shenzhen China"},{"name":"Key Laboratory of Brain Cognition and Emotional Health of Guangdong Higher Education Institutes Shenzhen University  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hualing","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Psychology Shenzhen University  Shenzhen China"},{"name":"Shenzhen Key Laboratory of Affective and Social Cognitive Science Shenzhen University  Shenzhen China"},{"name":"Key Laboratory of Brain Cognition and Emotional Health of Guangdong Higher Education Institutes Shenzhen University  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqi","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Psychology Shenzhen University  Shenzhen China"},{"name":"Shenzhen Key Laboratory of Affective and Social Cognitive Science Shenzhen University  Shenzhen China"},{"name":"Key Laboratory of Brain Cognition and Emotional Health of Guangdong Higher Education Institutes Shenzhen University  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jialin","family":"Fan","sequence":"additional","affiliation":[{"name":"School of Psychology Shenzhen University  Shenzhen China"},{"name":"Shenzhen Key Laboratory of Affective and Social Cognitive Science Shenzhen University  Shenzhen China"},{"name":"Key Laboratory of Brain Cognition and Emotional Health of Guangdong Higher Education Institutes Shenzhen University  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingfei","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Psychology Shenzhen University  Shenzhen China"},{"name":"Shenzhen Key Laboratory of Affective and Social Cognitive Science Shenzhen University  Shenzhen China"},{"name":"Key Laboratory of Brain Cognition and Emotional Health of Guangdong Higher Education Institutes Shenzhen University  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Xin","sequence":"additional","affiliation":[{"name":"School of Psychology Shenzhen University  Shenzhen China"},{"name":"Shenzhen Key Laboratory of Affective and Social Cognitive Science Shenzhen University  Shenzhen China"},{"name":"Key Laboratory of Brain Cognition and Emotional Health of Guangdong Higher Education Institutes Shenzhen University  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,17]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.12401"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1023\/a:1005653411471"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2025.106350"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2014.01.023"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1037\/t00742\u2010000"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2013.08.048"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v076.i01"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2823"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2011.03.023"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpsycho.2016.10.012"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/da.10113"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2005.11.074"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2003.10.009"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1027\/1618\u20103169.56.1.48"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.10010"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2014.10.015"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.02.043"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1037\/1528\u20103542.7.2.336"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469\u20108986.2007.00602.x"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.2145\u201009.2009"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.2001.81.2.629"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2018.05.031"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.13016"},{"key":"e_1_2_12_25_1","first-page":"316","volume-title":"The Oxford Handbook of Evolutionary Psychology and Behavioral Endocrinology","author":"Grebe N. M.","year":"2019"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2012.156"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2014.10.007"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755\u20105949.2008.00051.x"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhg111"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.09.038"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2015.08.027"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00031.2017"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380\u2010024\u201002871\u20104"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20528"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.11.030"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.3390\/bs12080262"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/2515245920951503"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469\u20108986.00081"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpsycho.2014.06.007"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpsycho.2014.05.007"},{"key":"e_1_2_12_41_1","volume-title":"An Introduction to the Event\u2010Related Potential Technique","author":"Luck S. J.","year":"2014"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.09.018"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2014.01.025"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006\u20108993(83)90478\u2010x"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhaa147"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2015.06.004"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0006\u20108993(97)01159\u20101"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/smi.2533"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/jne.13049"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2014.10.005"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhs306"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2020.03.008"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380\u2010020\u201000864\u20107"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1162\/jocn.2009.21257"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2014.00353"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2012.001"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2015.11.001"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.3402\/ejpt.v5.25338"},{"key":"e_1_2_12_59_1","volume-title":"Manual for the State\u2010Trait Anxiety Inventory","author":"Spielberger C. D.","year":"1983"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0024932"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23010150"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2008.05.006"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1503\/jpn.110089"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0079\u20106123(08)00422\u20106"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0896\u20106273(01)00328\u20102"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2013.00093"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2026.106628"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNR.0b013e3283587161"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1037\/\/0022\u20103514.54.6.1063"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhy295"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202001077"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380\u2010025\u201002898\u20101"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-32-9705-0_7"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2022.110531"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429\u2010018\u20101694\u20101"}],"container-title":["Psychophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/psyp.70342","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/psyp.70342","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/psyp.70342","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T16:41:55Z","timestamp":1782405715000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/psyp.70342"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":74,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1111\/psyp.70342"],"URL":"https:\/\/doi.org\/10.1111\/psyp.70342","archive":["Portico"],"relation":{},"ISSN":["0048-5772","1469-8986"],"issn-type":[{"value":"0048-5772","type":"print"},{"value":"1469-8986","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"2025-09-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70342"}}