{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:51:49Z","timestamp":1787161909078,"version":"build-2736575974"},"reference-count":45,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["VI.Vidi.191.045"],"award-info":[{"award-number":["VI.Vidi.191.045"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psychophysiology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Pupil responses shape the earliest stages of visual perception by regulating the amount of light that enters the eye. How this affects visual processing is still poorly understood. Here we present evidence that pupil constriction causes activity in the human retina and visual system, independently of visual stimulation. Healthy human participants (\n                    <jats:italic>N<\/jats:italic>\n                    \u2009=\u2009119) viewed brief visual stimuli (light increments or decrements) while pupil size, retinal activity (electroretinogram), and brain activity (electroencephalogram) were recorded. As expected, visual stimulation triggered an initial burst of retinal activity followed by pupil constriction (the pupil light response). Importantly, we used trial\u2010to\u2010trial variability in constriction latency to reveal a previously unknown retinal response that is locked to pupil constriction, rather than to visual stimulation. Presumably, and in line with similar findings in mice, this constriction\u2010locked retinal activity is a response to the sudden decrease in retinal light exposure that accompanies pupil constriction (although a contribution of iris muscle activity is not conclusively ruled out). A similar constriction\u2010locked response emerged later over visual cortex. Given these findings, an important open question is how the visual system maintains brightness constancy despite pupil\u2010induced retinal and cortical activity.\n                  <\/jats:p>","DOI":"10.1111\/psyp.70362","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T04:15:38Z","timestamp":1784780138000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pupil Constriction Causes Activity in the Human Retina and Visual System"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3379-8584","authenticated-orcid":false,"given":"Sebastiaan","family":"Math\u00f4t","sequence":"first","affiliation":[{"name":"Department of Psychology University of Groningen  Groningen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2507-2823","authenticated-orcid":false,"given":"Olaf","family":"Dimigen","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Groningen  Groningen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8940-8851","authenticated-orcid":false,"given":"Hakan","family":"Karsilar","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Groningen  Groningen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9959-5117","authenticated-orcid":false,"given":"Veera","family":"Ruuskanen","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Groningen  Groningen the 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