{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T10:40:26Z","timestamp":1761648026489},"reference-count":10,"publisher":"Wiley","issue":"s6","license":[{"start":{"date-parts":[[2012,12,24]],"date-time":"2012-12-24T00:00:00Z","timestamp":1356307200000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:title>Contents<\/jats:title><jats:p>A <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>almatian female presented with a history of vaginal bleeding and was diagnosed as having transmissible venereal tumour (<jats:styled-content style=\"fixed-case\">TVT<\/jats:styled-content>) after cytological examination of the vaginal growth revealed typical <jats:styled-content style=\"fixed-case\">TVT<\/jats:styled-content> cells. A cytology of the aspirate from multiple nodules in the skin near the abdominal and inguinal pair of mammary glands revealed similar cells suggestive of metastasis to skin of mammary region. Chemotherapy was initiated with weekly injections of vincristine sulphate (0.025\u00a0mg\/kg <jats:styled-content style=\"fixed-case\">BW<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> IV<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> SID<\/jats:styled-content>) and haematological examination was performed pre\u2010 and post\u2010treatment to assess the prognosis of the patient and side effects of the drug. The major side effects observed during the course of the treatment were high body temperature, mild neutropaenia and significant decrease in packed cell volume, haemoglobin, total leucocyte and erythrocyte count. Four weekly injections of vincristine were administered, and 4\u00a0weeks from initiation of treatment, the tumour and nodules were gone, suggesting complete recovery.<\/jats:p>","DOI":"10.1111\/rda.12105","type":"journal-article","created":{"date-parts":[[2012,12,24]],"date-time":"2012-12-24T06:03:59Z","timestamp":1356329039000},"page":"366-369","source":"Crossref","is-referenced-by-count":5,"title":["Successful Management of Metastatic Transmissible Venereal Tumour to Skin of Mammary Region"],"prefix":"10.1111","volume":"47","author":[{"given":"EE","family":"Varughese","sequence":"first","affiliation":[{"name":"Department of Veterinary Gynaecology and Obstetrics Guru Angad Dev Veterinary and Animal Sciences University Ludhiana Punjab India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"VK","family":"Singla","sequence":"additional","affiliation":[{"name":"Department of Veterinary Gynaecology and Obstetrics Guru Angad Dev Veterinary and Animal Sciences University Ludhiana Punjab India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U","family":"Ratnakaran","sequence":"additional","affiliation":[{"name":"Department of Veterinary Gynaecology and Obstetrics Guru Angad Dev Veterinary and Animal Sciences University Ludhiana Punjab India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"VK","family":"Gandotra","sequence":"additional","affiliation":[{"name":"Department of Veterinary Gynaecology and Obstetrics Guru Angad Dev Veterinary and Animal Sciences University Ludhiana Punjab India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,12,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098587000700604"},{"key":"e_1_2_8_3_1","first-page":"163","article-title":"Vincristine for treatment of transmissible venereal tumours in the dog","volume":"181","author":"Calvert CA","year":"1982","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006491918910"},{"key":"e_1_2_8_5_1","first-page":"183","article-title":"So\u2010called infectious sarcoma of the dog in an unusual anatomic situation","volume":"5","author":"Feldman WH","year":"1929","journal-title":"Am J Pathol"},{"key":"e_1_2_8_6_1","first-page":"854","article-title":"Occurrence of canine transmissible venereal tumour and evaluation of two treatments","volume":"70","author":"Gandotra VK","year":"1993","journal-title":"Indian Vet J"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/jcpa.1999.0366"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.79.3.67"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1952.tb39989.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0442.2005.00743.x"},{"key":"e_1_2_8_11_1","first-page":"1036","article-title":"Transmissible venereal tumor","volume":"19","author":"Rogers KS","year":"1997","journal-title":"Compend Contin Educ Pract Vet"}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Frda.12105","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.12105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T23:48:40Z","timestamp":1694648920000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.12105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":10,"journal-issue":{"issue":"s6","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["10.1111\/rda.12105"],"URL":"https:\/\/doi.org\/10.1111\/rda.12105","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"value":"0936-6768","type":"print"},{"value":"1439-0531","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12]]}}}