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Embryos were bisected and each pair of demi\u2010embryos was bilaterally transferred to recipients (n\u00a0=\u00a061) on day 7 of the oestrous cycle. At <jats:styled-content style=\"fixed-case\">ET<\/jats:styled-content> recipients were randomly assigned to treatment with 1500\u00a0IU h<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content> or to untreated controls. Higher (p\u00a0&lt;\u00a00.01) pregnancy rates on days 25, 42 and 63, and embryo survival rate on day 63 were observed in h<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content>\u2010treated cows with secondary <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> than in h<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content>\u2010treated cows without secondary <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> and in untreated cows. Pregnancy rates and embryo survival rate were similar in h<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content>\u2010treated cows without secondary <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> and untreated cows. Embryonic size on day 42 was not affected by treatment with h<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content>, presence of secondary <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> and type of pregnancy (single vs twin). Presence of secondary <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> increased (p\u00a0&lt;\u00a00.05) plasma <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><jats:sub>4<\/jats:sub> concentrations of pregnant cows on days 14, 19 and 25 but not thereafter and of non\u2010pregnant cows on days 14\u201321. Treatment with <jats:styled-content style=\"fixed-case\">hCG<\/jats:styled-content> and presence of secondary <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> had no effect on plasma <jats:styled-content style=\"fixed-case\">PSPB<\/jats:styled-content> concentrations, which were higher (p\u00a0&lt;\u00a00.05) in twin than in single pregnancies. In conclusion, secondary <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> induced by h<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content> treatment at <jats:styled-content style=\"fixed-case\">ET<\/jats:styled-content> significantly increased plasma <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><jats:sub>4<\/jats:sub> concentrations, the survival rate of demi\u2010embryos and the pregnancy rate of high\u2010yielding lactating dairy cows. Embryos were rescued beyond maternal recognition of pregnancy, but later embryonic survival, growth until implantation and placental <jats:styled-content style=\"fixed-case\">PSPB<\/jats:styled-content> secretion until day 63 of pregnancy were not affected by treatment or presence of secondary <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/rda.12138","type":"journal-article","created":{"date-parts":[[2013,1,16]],"date-time":"2013-01-16T11:09:28Z","timestamp":1358334568000},"page":"643-650","source":"Crossref","is-referenced-by-count":13,"title":["Secondary Corpora Lutea Induced by h<scp>CG<\/scp> Treatment Enhanced Demi\u2010Embryo Survival in Lactating High\u2010Yielding Dairy Cows"],"prefix":"10.1111","volume":"48","author":[{"given":"A","family":"Torres","sequence":"first","affiliation":[{"name":"Reproduction and Obstetrics Faculty of Veterinary Medicine CIISA Technical University of Lisbon Avenida da Universidade T\u00e9cnica Lisboa Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J Chagas e","family":"Silva","sequence":"additional","affiliation":[{"name":"Reproduction and Obstetrics Faculty of Veterinary Medicine CIISA Technical University of Lisbon Avenida da Universidade T\u00e9cnica Lisboa Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MC","family":"Deloche","sequence":"additional","affiliation":[{"name":"Department Recherche et Development UNCEIA Maisons Alfort France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Humblot","sequence":"additional","affiliation":[{"name":"Department Recherche et Development UNCEIA Maisons Alfort France"},{"name":"Division of Reproduction Department of Clinical Sciences Faculty of Veterinary Medicine and Agricultural Sciences SLU Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AEM","family":"Horta","sequence":"additional","affiliation":[{"name":"URGRMA INIA\u2010INRB Vale de Santar\u00e9m Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Lopes\u2010da\u2010Costa","sequence":"additional","affiliation":[{"name":"Reproduction and Obstetrics Faculty of Veterinary Medicine CIISA Technical University of Lisbon Avenida da Universidade T\u00e9cnica Lisboa Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,1,16]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2007.03.010"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gap095"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093-691X(90)90563-9"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD07204"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2004.10.019"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2007.01.004"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP-09-0152"},{"key":"e_1_2_8_9_1","doi-asserted-by":"crossref","first-page":"301","DOI":"10.2527\/jas1989.672301x","article-title":"Use of embryo transfer to induce twinning in beef cattle: embryo survival rate, gestation length, birth weight and weaning weight of calves","volume":"67","author":"Davis ME","year":"1989","journal-title":"J Anim Sci"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2009.11.027"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093-691X(93)90278-D"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.2527\/1992.7082309x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022-0302(78)83622-4"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.108.074336"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.110.085910"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0840437"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2005.03.003"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093-691X(92)90155-K"},{"key":"e_1_2_8_19_1","first-page":"23","volume-title":"Effect of Inducing Calvings on Calf Birth Weight","author":"Horta AEM","year":"1992"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0093-691X(01)00644-6"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0830215"},{"key":"e_1_2_8_22_1","unstructured":"JeanguyotN BarbatoO AzevedoPJ MalfattiA DebenedettiA HumblotP 2004:Use of a prot\u00e9ine de gestation Elisa for the detection of pregnancy in cattle and buffaloes. 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