{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T18:21:48Z","timestamp":1785522108526,"version":"3.56.0"},"reference-count":45,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,7,5]],"date-time":"2013-07-05T00:00:00Z","timestamp":1372982400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012352","name":"Universit\u00e0 degli Studi di Milano","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012352","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:title>Contents<\/jats:title><jats:p>Four different aquaporins (<jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>1, 2, 5 and 9), integral membrane water channels that facilitate rapid passive movement of water, were immuno\u2010localized in the excurrent ducts collected from sexually mature cats during orchiectomy. Aquaporins 1, 2 and 9, were immuno\u2010localized at distinct levels, whereas <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>5 was undetectable all along the feline genital tract. No immunoreactivity was present at the level of the <jats:italic>rete testis<\/jats:italic> with any of the antibodies tested. In the efferent ducts, <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>1\u2010immunoreactivity was strongly evidenced at the apical surface of the non\u2010ciliated cells, and <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>9\u2010immunoreactivity was shown at the periphery of both ciliated and non\u2010ciliated cells. Aquaporins 2 was absent in the <jats:italic>caput epididymidis<\/jats:italic>, either in the efferent ducts or in the epididymal duct. Otherwise, <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>2 was increasingly localized at the adluminal surface of principal cells from the <jats:italic>corpus<\/jats:italic> to the <jats:italic>cauda epididymidis<\/jats:italic> and more weakly in the vas deferens epithelium. The supranuclear zone of the epididymal principal cells was <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>9\u2010immunoreactive throughout the duct, with the exclusion of the vacuolated sub\u2010region of the <jats:italic>caput<\/jats:italic> and with higher reaction intensity in the <jats:italic>cauda<\/jats:italic> region. <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>1 was present in the blood vessels all along the genital tract. <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>1 was expressed also in the smooth muscle layer of the vas deferens. The tested <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content> molecules showed a different expression pattern in comparison with laboratory mammals, primates and the dog, unique other carnivore species studied to date. The present information is possibly useful in regard to the regional morphology of the feline epididymis and correlated functions, which are still a matter of debate.<\/jats:p>","DOI":"10.1111\/rda.12213","type":"journal-article","created":{"date-parts":[[2013,7,5]],"date-time":"2013-07-05T10:34:13Z","timestamp":1373020453000},"page":"17-26","source":"Crossref","is-referenced-by-count":24,"title":["Immunolocalization of Aquaporin Water Channels in the Domestic Cat Male Genital Tract"],"prefix":"10.1111","volume":"49","author":[{"given":"S","family":"Arrighi","sequence":"first","affiliation":[{"name":"Laboratory of Anatomy Department of Health, Animal Science and Food Safety Universit\u00e0 degli Studi di Milano Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Aralla","sequence":"additional","affiliation":[{"name":"Laboratory of Anatomy Department of Health, Animal Science and Food Safety Universit\u00e0 degli Studi di Milano Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2002.020818"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0531.2011.01886.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2009.01.023"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2012.02.017"},{"key":"e_1_2_8_6_1","first-page":"7","article-title":"Ultrastructural study on the epithelium lining ductus epididymis in adult cats (Felis catus)","volume":"97","author":"Arrighi S","year":"1986","journal-title":"Arch Biol"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2010.06.039"},{"key":"e_1_2_8_8_1","first-page":"433","article-title":"Absorptive activities of the efferent ducts evaluated by the immunolocalization of aquaporin water channels and lectin histochemistry in adult cats","volume":"25","author":"Arrighi S","year":"2010","journal-title":"Histol Histopathol"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0531.2007.00780.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1262\/jrd.45.151"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1939-4640.2002.tb02243.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-012-1381-0"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0531.2006.00817.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.1994.sp003817"},{"key":"e_1_2_8_15_1","first-page":"1","article-title":"Fluid and electrolyte reabsorption in the ductuli efferentes testis","volume":"53","author":"Clulow J","year":"1998","journal-title":"J Reprod Fertil Suppl"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0610163"},{"key":"e_1_2_8_17_1","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1093\/humupd\/dmn055","article-title":"New insights into epididymal biology and function","volume":"15","author":"Cornwall GA","year":"2009","journal-title":"Hum Reprod Update"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2006.06.026"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.105.044735"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/19396368.2012.663233"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.20611"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-008-0592-x"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4320(00)00106-8"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.139.9.3935"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.104.036426"},{"key":"e_1_2_8_26_1","first-page":"39","article-title":"Some aspects of structure and function in the mammalian epididymis","volume":"13","author":"Glover TD","year":"1971","journal-title":"J Reprod Fertil Suppl"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033583506004458"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.110.012831"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1939-4640.2004.tb02820.x"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1369\/jhc.2008.951947"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dml035"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0264.2007.00827.x"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2005.08.016"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0531.2012.02079.x"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1998.275.1.C216"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod66.4.1161"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1042\/BC20040078"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod65.2.384"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod66.6.1716"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP-09-0284"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-4-51"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.16.9660"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0531.2009.01391.x"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.5603\/FHC.2011.0065"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0264.2004.00564.x"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2012.02.002"}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Frda.12213","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Frda.12213","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.12213","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/rda.12213","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.12213","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T07:49:10Z","timestamp":1693900150000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.12213"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,5]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["10.1111\/rda.12213"],"URL":"https:\/\/doi.org\/10.1111\/rda.12213","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"value":"0936-6768","type":"print"},{"value":"1439-0531","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,5]]}}}