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In acute prostatitis, the blood\u2013prostate barrier is broken, thus facilitating the penetration of antibiotics, whereas in chronic prostatitis, the barrier prevents the penetration of many drugs into the gland. The selection of antibiotic agents is based on the sensitivity test and the drug's ability to penetrate into the gland. Many protocols for the treatment of<jats:styled-content style=\"fixed-case\">BPH<\/jats:styled-content>are available. In non\u2010breeding dogs, surgical and optionally pharmacological castration by means of Gn<jats:styled-content style=\"fixed-case\">RH<\/jats:styled-content>agonists may be performed. In breeding dogs, drugs retaining fertility are used. Recently, androgen receptor antagonistic treatment with osaterone acetate has been applied. Other drugs used for<jats:styled-content style=\"fixed-case\">BPH<\/jats:styled-content>treatment include progestagens, oestrogens, antioestrogens and 5<jats:italic>\u03b1<\/jats:italic>\u2010reductase inhibitors. Some of these compounds may provoke severe side effects. The efficiency of Gn<jats:styled-content style=\"fixed-case\">RH<\/jats:styled-content>antagonists used for the treatment of prostatic diseases, such as neoplasia and<jats:styled-content style=\"fixed-case\">BPH<\/jats:styled-content>, in humans has been recently investigated in dogs. This androgen deprivation therapy (<jats:styled-content style=\"fixed-case\">ADT<\/jats:styled-content>) is devoid of an initial exacerbation of androgen\u2010dependent symptoms, which is typical for Gn<jats:styled-content style=\"fixed-case\">RH<\/jats:styled-content>agonistic treatment. In many cases,<jats:styled-content style=\"fixed-case\">BPH<\/jats:styled-content>and prostatitis must be treated simultaneously as these conditions may develop in combination.<\/jats:p>","DOI":"10.1111\/rda.12297","type":"journal-article","created":{"date-parts":[[2014,6,20]],"date-time":"2014-06-20T12:45:35Z","timestamp":1403268335000},"page":"8-15","source":"Crossref","is-referenced-by-count":51,"title":["Pharmacological Treatment for Common Prostatic Conditions in Dogs \u2013 Benign Prostatic Hyperplasia and Prostatitis: an Update"],"prefix":"10.1111","volume":"49","author":[{"given":"W","family":"Ni\u017ca\u0144ski","sequence":"first","affiliation":[{"name":"Department of Reproduction Faculty of Veterinary Medicine Wroc\u0142aw University of Environmental and Life Sciences Wroc\u0142aw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X","family":"Levy","sequence":"additional","affiliation":[{"name":"CRECS Isle Jourdain Gers 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