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Many studies highlighted the importance of e<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content> treatment following fixed\u2010time artificial insemination in improving follicular growth, ovulation and pregnancy rates in cattle. Moreover, e<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content> has been implicated in angiogenesis, leading to important changes in uterine blood flow and vascularisation. However, there is still a lack of information regarding the specific alterations induced by e<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content> upon glandular and vascular characteristics of bovine uterus. To investigate the influence of e<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content> on: uterine thickness and area; uterine artery diameter and area; uterine vascular and gland density; and the expression of the <jats:styled-content style=\"fixed-case\">VEGFA<\/jats:styled-content>\u2010system, the uteri of crossbred beef cows were collected. All cows were submitted to follicular wave emergence synchronization. On day four of protocol, cows submitted to superovulation (n\u00a0=\u00a06) received 2000\u00a0IU e<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content>, on day eight, after expected follicular deviation, cows submitted to stimulatory treatment (n\u00a0=\u00a05) received 400\u00a0IU e<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content>. Control cows (n\u00a0=\u00a05) did not receive e<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content>. On day five po cows were subjected to ultrassonographic evaluation and slaughtered for uterine tissue sampling on day six po. Uterine vessels and glands were quantified by the counting point stereological method. The <jats:styled-content style=\"fixed-case\">VEGFA<\/jats:styled-content>\u2010system was localized in different cellular types, showing no qualitative or quantitative differences in the site of expression or the intensity of the positive signal among the groups. Vascular density was decreased in the endometrium of stimulated and myometrium of superovulated cows compared with the control ones, which showed higher vascular density in the myometrium and endometrium of the ipsilateral uterine horn. The uterine gland density was higher in superovulated compared with stimulated and control cows. Thus, we can infer that stimulatory or superovulatory treatments with e<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content> influence the vascular density in the endometrium and myometrium in cattle.<\/jats:p>","DOI":"10.1111\/rda.12307","type":"journal-article","created":{"date-parts":[[2014,4,2]],"date-time":"2014-04-02T05:14:54Z","timestamp":1396415694000},"page":"453-462","source":"Crossref","is-referenced-by-count":12,"title":["Treatment with <scp>eCG<\/scp> Decreases the Vascular Density and Increases the Glandular Density of the Bovine Uterus"],"prefix":"10.1111","volume":"49","author":[{"given":"J","family":"Mona e Pinto","sequence":"first","affiliation":[{"name":"Department of Surgery Faculty of Veterinary Medicine and Animal Sciences University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"V","family":"Pavanelo","sequence":"additional","affiliation":[{"name":"Department of Surgery Faculty 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