{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T15:13:54Z","timestamp":1769008434829,"version":"3.49.0"},"reference-count":58,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,3,30]],"date-time":"2017-03-30T00:00:00Z","timestamp":1490832000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Contents<\/jats:title><jats:p>Aquaporins (<jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>s) are channel proteins that facilitate the transepithelial and bidirectional movement of water. <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>9 is an aquaporin that is expressed in the mammalian epididymis. This water transport contributes to epididymal sperm concentration. This study aimed to examine the morphology of epididymal epithelium in piglets and boars, as well as the expression and immunolocalization of <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>9. The piglets presented an epididymal epithelium in differentiation with principal, basal and apical cells. The cellular population of the epididymal epithelium in boars consisted of principal, basal, apical, clear and narrow cells. The migratory cells known as halo cells were observed in the epididymis of both piglets and boars. <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>9 expression presented differences between piglets and boars. Moderate intensity of <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>9 immunoreaction was observed in the apical border of the epididymal epithelium of the <jats:italic>caput<\/jats:italic> and <jats:italic>cauda<\/jats:italic> regions in the piglet epididymis. A moderate\u2010to\u2010intense reaction for <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>9 was observed in the nuclei of epithelial cells of the three epididymal regions in the boar epididymis. The region of the <jats:italic>cauda<\/jats:italic> epididymis showed reactivity for <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>9 also in the apical border of the epithelium. It is believed that the <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>9 is already functional in piglets at only 1\u00a0week of age and is more active, playing a pivotal role in the <jats:italic>caput<\/jats:italic> and <jats:italic>cauda<\/jats:italic> regions of the epididymis. Moreover, the intense <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>9 expression in the apical border of epithelial cells in the <jats:italic>cauda<\/jats:italic> region of the boar epididymis suggests a higher performance of <jats:styled-content style=\"fixed-case\">AQP<\/jats:styled-content>9 in this region, where sperm complete their maturation process, stored and concentrated.<\/jats:p>","DOI":"10.1111\/rda.12957","type":"journal-article","created":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T06:44:59Z","timestamp":1490942699000},"page":"617-624","source":"Crossref","is-referenced-by-count":18,"title":["Aquaporin 9 is expressed in the epididymis of immature and mature pigs"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0837-9612","authenticated-orcid":false,"given":"BC","family":"Schimming","sequence":"first","affiliation":[{"name":"Department of Anatomy Institute of Biosciences S\u00e3o Paulo State University 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