{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:13:08Z","timestamp":1777525988183,"version":"3.51.4"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,3,30]],"date-time":"2017-03-30T00:00:00Z","timestamp":1490832000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31672465"],"award-info":[{"award-number":["31672465"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Contents<\/jats:title><jats:p>Oestrous signs affect timely mating and reproductive efficiency in swine breeding herds. To study the genetic difference of oestrous signs between Chinese and European pigs, 100 Landrace\u2010Large White (<jats:styled-content style=\"fixed-case\">LLW<\/jats:styled-content>) cross gilts and 50 Chinese Mi gilts were assessed for oestrous signs and the concentrations of serum estradiol\u201017\u03b2 and progesterone were determined. The genotype of 39 single nucleotide polymorphisms (<jats:styled-content style=\"fixed-case\">SNP<\/jats:styled-content>s) in 11 oestrogen metabolism and function\u2010related genes was determined by Sequenom <jats:styled-content style=\"fixed-case\">iPLEX<\/jats:styled-content> platform. Compared with <jats:styled-content style=\"fixed-case\">LLW<\/jats:styled-content> gilts, Mi gilts had longer time of standing reflex (<jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>.001), higher scores of vulva reddening (<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.001) and greater serum estradiol\u201017\u03b2 concentration (<jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>.01). Gilts with greater serum estradiol\u201017\u03b2 concentrations also had greater (<jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>.05) scores for oestrous signs. Genetic polymorphisms of nine genes in oestrogen metabolism pathways had significant differences (<jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>.05) between <jats:styled-content style=\"fixed-case\">LLW<\/jats:styled-content> and Mi gilts. There were three and six haploblocks of <jats:styled-content style=\"fixed-case\">SNP<\/jats:styled-content>s in <jats:styled-content style=\"fixed-case\">LLW<\/jats:styled-content> and Mi, respectively. Compared with <jats:styled-content style=\"fixed-case\">LLW<\/jats:styled-content>, the distribution of haplotypes was more centralized in Mi pigs. Genetic polymorphisms of oestrogen metabolism\u2010related genes have considerable differences between Chinese Mi and European <jats:styled-content style=\"fixed-case\">LLW<\/jats:styled-content> pigs. Because of the important roles of oestrogen during the oestrus, some genes of oestrogen metabolism pathway could be considered as candidate genes for oestrous signs.<\/jats:p>","DOI":"10.1111\/rda.12964","type":"journal-article","created":{"date-parts":[[2017,3,30]],"date-time":"2017-03-30T10:12:20Z","timestamp":1490868740000},"page":"696-700","source":"Crossref","is-referenced-by-count":4,"title":["Genetic differences in oestrous signs and oestrogen metabolism\u2010related genes between Chinese Mi and European Landrace\u2010Large White pigs"],"prefix":"10.1111","volume":"52","author":[{"given":"Q","family":"Chu","sequence":"first","affiliation":[{"name":"College of Animal Science and Technology Nanjing Agricultural University  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Liang","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Nanjing Agricultural University  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2857-8536","authenticated-orcid":false,"given":"B","family":"Zhou","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Nanjing Agricultural University  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0830723"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.applanim.2007.04.004"},{"key":"e_1_2_5_4_1","first-page":"247","article-title":"Genetic basis of prolificacy in Meishan pigs","volume":"48","author":"Haley C.","year":"1993","journal-title":"Journal of Reproduction and Fertility Supplement"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0970475"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1500141"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1001012"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2005.12.015"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2011.02.025"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2011.08.015"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod24.2.223"},{"key":"e_1_2_5_12_1","first-page":"88","article-title":"Study on the relationships of intravaginal electrical impedance and plasma level of progesterone and estradiol\u201017b in estrus synchronized sows in prediction of the optimal insemination time in pig","volume":"45","author":"Yilma T.","year":"2011","journal-title":"Indian Journal of Animal Research"}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Frda.12964","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.12964","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T12:47:35Z","timestamp":1694954855000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.12964"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,30]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["10.1111\/rda.12964"],"URL":"https:\/\/doi.org\/10.1111\/rda.12964","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"value":"0936-6768","type":"print"},{"value":"1439-0531","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,30]]}}}