{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T22:34:22Z","timestamp":1793054062809,"version":"4.5.0"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,10,8]],"date-time":"2018-10-08T00:00:00Z","timestamp":1538956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Contents<\/jats:title><jats:p>Recently, a new molecule, kisspeptin (Kp), and in particular Kisspeptin 10 (Kp10), was implicated in stimulating the hypothalamic\u2013pituitary\u2013gonadal axis. The aim of this study was to evaluate circulating Kp10 levels in the early post\u2013partum period of the dairy cow. Blood samples were collected from 40 dairy cows, at 10 (T10), 12 (T12), 14 (T14) and 16 (T16) days after calving. Progesterone (P4) levels were evaluated using <jats:styled-content style=\"fixed-case\">ELISA<\/jats:styled-content>, and levels of oestrogens (E2) and Kp were evaluated using a radio\u2010immunologic method. After an initial plateau, Kp10 significantly increased at T14 and decreased at T16. The P4 and E2 mean serum values remained in the physiological range. It is likely that Kp10 enhanced hypothalamic Gn<jats:styled-content style=\"fixed-case\">RH<\/jats:styled-content> release as well as pituitary gonadotropin secretion, thus promoting follicular growth and the increase in E2 levels, which might have further enhanced Kp10 release through a positive feedback loop. To our best knowledge, this is the first report on the range of Kp10 blood concentration during the early post\u2013partum period in the dairy cow. The results of our study will increase our current understanding of the complex neuro\u2010endocrine crosstalk underlying the resumption of ovarian cyclicity in the dairy cow.<\/jats:p>","DOI":"10.1111\/rda.13325","type":"journal-article","created":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T13:34:20Z","timestamp":1535722460000},"page":"195-198","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Kisspeptin in the early post\u2013partum of the dairy cow"],"prefix":"10.1111","volume":"54","author":[{"given":"Annalisa","family":"Rizzo","sequence":"first","affiliation":[{"name":"Department of Veterinary Medicine University of Bari Aldo Moro Valenzano (BA) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmondo","family":"Ceci","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine University of Bari Aldo Moro Valenzano (BA) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Ciro","family":"Guaricci","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine University of Bari Aldo Moro Valenzano (BA) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1141-3084","authenticated-orcid":false,"given":"Raffaele Luigi","family":"Sciorsci","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine University of Bari Aldo Moro Valenzano (BA) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,8]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Veterinary reproduction and obstetrics","author":"Arthur G. 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Tri\u2010State Dairy Nutrition Conference April 20\u201021."},{"key":"e_1_2_8_10_1","first-page":"29","article-title":"Kisspeptin and bovine follicular cysts","volume":"54","author":"Rizzo A.","year":"2018","journal-title":"Veterinaria Italiana"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.111.091538"},{"key":"e_1_2_8_12_1","first-page":"132","article-title":"KISS\u20101 system and reproduction: Comparative aspects and roles in the control of female gonadotropic axis in mammals","volume":"153","author":"Roa J.","year":"2007","journal-title":"Science"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2005-1463"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0880569"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac051437y"},{"key":"e_1_2_8_16_1","unstructured":"Tamanini C.(1997).Endocrinologia del postpartum e ripristino dell'attivit\u00e0 ovarica. Atti delle Giornate Buiatriche 11\u201327."}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Frda.13325","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.13325","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T20:24:48Z","timestamp":1694723088000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.13325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,8]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1111\/rda.13325"],"URL":"https:\/\/doi.org\/10.1111\/rda.13325","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"value":"0936-6768","type":"print"},{"value":"1439-0531","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,8]]},"assertion":[{"value":"2018-07-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}