{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:19:30Z","timestamp":1787015970941,"version":"build-2736575974"},"reference-count":10,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,4,14]],"date-time":"2019-04-14T00:00:00Z","timestamp":1555200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Contents<\/jats:title>\n                  <jats:p>Ovarian teratomas are occasionally reported in dogs; the rarest type is the monophasic teratoma, composed of tissues originating from only one germ layer. Canine endometrial adenocarcinomas are also rare in dogs and mainly affect geriatric females. This report describes the case of co\u2010existing ovarian teratoma and uterine adenocarcinoma in a 10\u2010year\u2010old nulliparous female Boxer presented with lethargy, anorexia and purulent vaginal discharge. Abdominal ultrasonography evidenced pyometra and a mass in the left ovary. This was composed of a uniform whitish tissue with multiple cystic structures. The histology revealed an atrophy of the ovarian parenchyma, compressed by a proliferation of well\u2010differentiated nervous tissue staining positively to vimentin, S100 and neuronal specific enolase (NSE), and negatively to keratin and inhibin. The left uterine horn, whose diameter was markedly increased, showed foci of endometrial cellular atypia, evident nucleoli and mitoses, at light microscopy. To our best knowledge, this is the first report of a co\u2010existing ovarian monophasic teratoma and endometrial adenocarcinoma, two rare reproductive neoplasia in dogs.<\/jats:p>","DOI":"10.1111\/rda.13430","type":"journal-article","created":{"date-parts":[[2019,3,25]],"date-time":"2019-03-25T03:41:47Z","timestamp":1553485307000},"page":"1044-1049","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Co\u2010existing monophasic teratoma and uterine adenocarcinoma in a female dog"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9473-5283","authenticated-orcid":false,"given":"Maria dos Anjos","family":"Pires","sequence":"first","affiliation":[{"name":"Animal and Veterinary Research Centre (CECAV) University of Tr\u00e1s\u2010os\u2010Montes and Alto Douro (UTAD) Vila Real Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Carlos","family":"Catarino","sequence":"additional","affiliation":[{"name":"Universidade Lusofona de Humanidades e Tecnologias, Medicina Veterin\u00e1ria Lisboa Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3976-1619","authenticated-orcid":false,"given":"Hugo","family":"Vilhena","sequence":"additional","affiliation":[{"name":"Animal and Veterinary Research Centre (CECAV) University of Tr\u00e1s\u2010os\u2010Montes and Alto Douro (UTAD) Vila Real Portugal"},{"name":"Baixo Vouga Veterinary Hospital \u00c1gueda Portugal"},{"name":"Department of Veterinary Medicine, Centre for Investigation Vasco da Gama (CIVG) Vasco da Gama University School Coimbra Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana","family":"Faim","sequence":"additional","affiliation":[{"name":"University Veterinary Hospital of Coimbra Coimbra Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiago","family":"Neves","sequence":"additional","affiliation":[{"name":"University Veterinary Hospital of Coimbra Coimbra Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreia","family":"Freire","sequence":"additional","affiliation":[{"name":"University Veterinary Hospital of Coimbra Coimbra Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1912-1457","authenticated-orcid":false,"given":"Fernanda","family":"Seixas","sequence":"additional","affiliation":[{"name":"Animal and Veterinary Research Centre (CECAV) University of Tr\u00e1s\u2010os\u2010Montes and Alto Douro (UTAD) Vila Real Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2673-2758","authenticated-orcid":false,"given":"Leonor","family":"Orge","sequence":"additional","affiliation":[{"name":"Animal and Veterinary Research Centre (CECAV) University of Tr\u00e1s\u2010os\u2010Montes and Alto Douro (UTAD) Vila Real Portugal"},{"name":"Pathology Laboratory UEISPSA, Instituto Nacional de Investiga\u00e7\u00e3o Agr\u00e1ria e Veterin\u00e1ria (INIAV), I.P. Oeiras Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5225-4510","authenticated-orcid":false,"given":"Rita","family":"Payan\u2010Carreira","sequence":"additional","affiliation":[{"name":"Animal and Veterinary Research Centre (CECAV) University of Tr\u00e1s\u2010os\u2010Montes and Alto Douro (UTAD) Vila Real Portugal"},{"name":"Department of Veterinary Medicine, School of Sciences and Technology University of \u00c9vora \u00c9vora Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.5326\/JAAHA-MS-5809"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098588502200204"},{"key":"e_1_2_7_4_1","first-page":"32","volume-title":"Histological classification of tumors of genital system of domestic animals","author":"Kennedy P.","year":"1998"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.4142\/jvs.2017.18.3.407"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.62.793"},{"key":"e_1_2_7_7_1","first-page":"1","volume-title":"Histopathology","author":"Payan\u2010Carreira R.","year":"2016"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0531.2008.01243.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/rda.12090"},{"key":"e_1_2_7_10_1","first-page":"610","volume-title":"Withrow and MacEwen\u2019s small animal clinical oncology","author":"Saba C.","year":"2012"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/rda.12497"}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.13430","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/rda.13430","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.13430","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T13:35:36Z","timestamp":1694266536000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.13430"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,14]]},"references-count":10,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1111\/rda.13430"],"URL":"https:\/\/doi.org\/10.1111\/rda.13430","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"value":"0936-6768","type":"print"},{"value":"1439-0531","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,14]]},"assertion":[{"value":"2018-11-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}