{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T01:01:50Z","timestamp":1792285310254,"version":"4.4.0"},"reference-count":9,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,8,10]],"date-time":"2019-08-10T00:00:00Z","timestamp":1565395200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["06\/50485-7 and 05\/57301-6"],"award-info":[{"award-number":["06\/50485-7 and 05\/57301-6"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>For the neonatal patient, precocity of diagnosis is crucial for effectiveness of medical approach. However, the newborn has its own physiological peculiarities due to ongoing adaptive mechanism for extrauterine life and deserves special attention in order to underline a specific management or clinical approach. The objective of this work was to verify clinical adaptations and biochemical balance of neonates during immediate period, with special reference to haematological, renal and metabolic functions. Neonatal puppies (<jats:italic>n<\/jats:italic>\u00a0=\u00a051) were physically examined for vitality and rectal temperature at birth, 5 and 60\u00a0min post\u2010birth. Blood was collected at birth and 60\u00a0min post\u2010birth for analysis of glucose, sodium, potassium, chlorine, blood urea nitrogen (BUN), haematocrit and haemoglobin. Neonatal vitality was lower at birth compared with 5\u00a0min and 60\u00a0min post\u2010birth. Progressive decline in rectal temperature (36.5\u00a0\u00b1\u00a00.3\u00b0C, 34.2\u00a0\u00b1\u00a00.2\u00b0C, 32.3\u00a0\u00b1\u00a00.5\u00b0C) was observed at birth, 5\u00a0min and 60\u00a0min post\u2010birth, respectively. Puppies presented slight hyponatremia (140.7\u00a0\u00b1\u00a00.5\u00a0mmol\/L) at birth and hypopotassemia (3.5\u00a0\u00b1\u00a00.1\u00a0mmol\/L) and blood urea nitrogen (13.1\u00a0\u00b1\u00a00.7\u00a0mg\/dl) during the first hour, and high haematocrit (45.1\u00a0\u00b1\u00a01.0%) and haemoglobin (15.3\u00a0\u00b1\u00a00.3\u00a0g\/dl) concentration. In conclusion, puppies had rapid evolution of vitality. Marked decrease in rectal temperature occurred at 5\u00a0min post\u2010birth. Haematological values of neonates immediately after birth reflected mainly the dam's blood status, not being useful for a blood panel at this time point. The peculiar pattern of BUN, sodium and potassium observed during transition period, suggested that specific reference range should be considered for neonatal puppies.<\/jats:p>","DOI":"10.1111\/rda.13534","type":"journal-article","created":{"date-parts":[[2019,7,29]],"date-time":"2019-07-29T23:23:55Z","timestamp":1564442635000},"page":"1419-1422","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Haematological and biochemical analysis of healthy neonatal puppies during the immediate foetal\u2010to\u2010neonatal transition"],"prefix":"10.1111","volume":"54","author":[{"given":"Cristina F\u00e1tima","family":"L\u00facio","sequence":"first","affiliation":[{"name":"Department of Animal Reproduction, School of Veterinary Medicine and Animal Science University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liege Cristina","family":"Garcia Silva","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction, School of Veterinary Medicine and Animal Science University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8198-2223","authenticated-orcid":false,"given":"Camila Infantosi","family":"Vannucchi","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction, School of Veterinary Medicine and Animal Science University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,10]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"O sistema hematopoi\u00e9tico. Pediatria veterin\u00e1ria em c\u00e3es e gatos at\u00e9 6 meses de idades","author":"Bounous D. I.","year":"1993"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-198705000-00015"},{"key":"e_1_2_9_4_1","volume-title":"Schalm's Veterinary Hematology","author":"Feldman B. F.","year":"2000"},{"key":"e_1_2_9_5_1","volume-title":"Clinical Biochemistry of Domestic Animals","author":"Kaneko J.","year":"2008"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-173-41637"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(99)50085-5"},{"key":"e_1_2_9_8_1","volume-title":"Per\u00edodo Neonatal. Neonatologia e pediatria canina e felina","author":"Pratz A.","year":"2005"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000242132"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2018.02.011"}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.13534","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/rda.13534","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.13534","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T12:28:43Z","timestamp":1694176123000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.13534"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,10]]},"references-count":9,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1111\/rda.13534"],"URL":"https:\/\/doi.org\/10.1111\/rda.13534","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"value":"0936-6768","type":"print"},{"value":"1439-0531","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,10]]},"assertion":[{"value":"2019-05-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}