{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:34:05Z","timestamp":1791225245956,"version":"4.1.0"},"reference-count":59,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,5,26]],"date-time":"2020-05-26T00:00:00Z","timestamp":1590451200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The environmental temperature increased during summer and decreased during winter to the limits that might negatively affect animal and human reproduction. The responses of Egyptian rams to either hot or cold climatic conditions were studied in six mature rams subjected to weekly testicular Doppler ultrasonographic examination, blood sampling, seminal plasma collection and semen evaluation. The maximum environmental temperature and the relative humidity were used to classify the climatic condition according to the heat stress equation of sheep into hot months where temperature\u2013humidity index (THI) was &gt;26 (31.67\u00a0\u00b1\u00a00.54), and cold months where THI was &lt;22 (18.39\u00a0\u00b1\u00a00.41). Testosterone, estradiol, superoxide dismutase (SOD), glutathione peroxidase (GPX) and lipid peroxide product (malondialdehyde, MDA) were measured in both blood and seminal plasma, while catalase (CAT) and reduced glutathione (GSH) were measured in blood and seminal plasma, respectively. Results revealed that, during the hot months, rams displayed significantly decreased testicular blood flow, increased seminal plasma MDA, decreased seminal plasma (SOD, GPx and GSH) and blood CAT antioxidant enzymes. The present study evidenced two novel findings: (a) the marked decrease in testicular blood flow volume, that is remarkable increase in both resistive index (RI) and pulsatility index (PI) values, during hot months could be negatively affected both seminal plasma enzymatic activities and seminal attributes, and (b) the SOD and GPx activities in seminal plasma of such animals were suitable predictive markers for seminal attribute evaluation.<\/jats:p>","DOI":"10.1111\/rda.13696","type":"journal-article","created":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T15:50:20Z","timestamp":1588780220000},"page":"861-869","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Seasonal variation in testicular blood flow dynamics and their relation to systemic and testicular oxidant\/antioxidant biomarkers and androgens in rams"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1806-2368","authenticated-orcid":false,"given":"Mohamed G.","family":"Hedia","sequence":"first","affiliation":[{"name":"Department of Theriogenology Faculty of Veterinary Medicine Cairo University Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed S.","family":"El\u2010Belely","sequence":"additional","affiliation":[{"name":"Department of Theriogenology Faculty of Veterinary Medicine Cairo University Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayed T.","family":"Ismail","sequence":"additional","affiliation":[{"name":"Department of Theriogenology Faculty of Veterinary Medicine Cairo University Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal M.","family":"Abo El\u2010Maaty","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction and AI, Veterinary Division National Research Center Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(84)05016-3"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2007.00559.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/and.12773"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrd.1120230108"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/and.12951"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.11606\/issn.2318-3659.v50i5p384-395"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2005.66.1415"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0093-691X(03)00144-4"},{"issue":"1","key":"e_1_2_9_10_1","first-page":"31","article-title":"Age and season effects on sexual parameters in mature rams used in artificial insemination center (Algeria)","volume":"18","author":"Belkhiri Y.","year":"2017","journal-title":"Global Veterinaria"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-7-125"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.2002.03033.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD17533"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1262\/jrd.20014"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-8-59"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2004.06.006"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-013-2801-4"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smallrumres.2015.06.014"},{"key":"e_1_2_9_19_1","first-page":"258","article-title":"Methods of Enzymatic Analysis (Bergmeyen, H.V.Ed.)","volume":"3","author":"Goldberg D. 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