{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T09:30:43Z","timestamp":1768642243651,"version":"3.49.0"},"reference-count":43,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,10,4]],"date-time":"2020-10-04T00:00:00Z","timestamp":1601769600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of the present study was to evaluate the biochemical profile and reproductive performance in postpartum dairy cows with clinical metritis. The research was carried out using performed on 213 pluriparous lactating cows from two dairy herds in southeast Brazil. Dairy cows were assigned into a group of healthy cows (<jats:italic>n<\/jats:italic>\u00a0=\u00a0147) and cows with metritis (<jats:italic>n<\/jats:italic>\u00a0=\u00a066). Blood samples to assess serum albumin, cholesterol, fibrinogen, calcium, gamma\u2010glutammyltransferase (GGT), aspartate aminotransferase (AST) and \u03b2\u2010hydroxybutyrate (BHBA) concentrations were performed on day 8\u00a0\u00b1\u00a02 postpartum. Metritic cows had lower (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05) serum albumin, cholesterol and calcium concentration, and higher (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05) GGT and AST activity, and BHBA and fibrinogen concentrations when compared to the healthy group. The calving\u2010to\u2010conception interval and services per pregnancy were higher in metritic cows (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.01) than in healthy cows and the conception rate at first service was lower in metric group (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.01). Variable importance in projection plots demonstrated that cholesterol was the main discriminator between metritic and healthy cows. Our results indicated alterations in the biochemical profile and impaired reproduction performance in metritic cows.<\/jats:p>","DOI":"10.1111\/rda.13815","type":"journal-article","created":{"date-parts":[[2020,9,4]],"date-time":"2020-09-04T10:45:15Z","timestamp":1599216315000},"page":"1599-1606","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Alterations in biochemical profiles and reproduction performance in postpartum dairy cows with metritis"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1039-371X","authenticated-orcid":false,"given":"Renan Braga","family":"Paiano","sequence":"first","affiliation":[{"name":"Department of Animal Reproduction School of Veterinary Medicine and Animal Sciences University of S\u00e3o Paulo S\u00e3o Paulo Brazil"},{"name":"Department of Anatomy of Domestic and Wild Animals School of Veterinary Medicine and Animal Sciences University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8103-5720","authenticated-orcid":false,"given":"Daniela Becker","family":"Birgel","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine College of Animal Science and Food Engineering University of S\u00e3o Paulo Pirassununga Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5664-0096","authenticated-orcid":false,"given":"Jeannine","family":"Bonilla","sequence":"additional","affiliation":[{"name":"Department of Food Engineering College of Animal Science and Food Engineering University of S\u00e3o Paulo Pirassununga Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9079-0549","authenticated-orcid":false,"given":"Eduardo Harry","family":"Birgel Junior","sequence":"additional","affiliation":[{"name":"Department of Anatomy of Domestic and Wild Animals School of Veterinary Medicine and Animal Sciences University of S\u00e3o Paulo S\u00e3o Paulo Brazil"},{"name":"Department of Veterinary Medicine College of Animal Science and Food Engineering University of S\u00e3o Paulo Pirassununga Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,4]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1071\/AN14863"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022-0302(04)73446-3"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2015-9683"},{"key":"e_1_2_9_5_1","doi-asserted-by":"crossref","first-page":"11701","DOI":"10.3168\/jds.2019-17025","article-title":"Long\u2010term effects of postpartum clinical disease on milk production, reproduction, and culling of dairy cows","volume":"102","author":"Carvalho M. 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