{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T02:14:37Z","timestamp":1782440077659,"version":"3.54.5"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T00:00:00Z","timestamp":1605571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>For successful batch farrowing, porcine oestrus and ovulation must be synchronized using fixed\u2010time artificial insemination (FTAI). However, exogenous gonadotropins, which are currently used in FTAI, negatively affect gilt ovulation. Here, we aimed to improve sexually mature gilt superovulation efficiency using passive immunization against inhibin during FTAI. Altrenogest\u2010treated gilts were challenged with 10\u00a0ml anti\u2010inhibin serum (AIS group, <jats:italic>n<\/jats:italic>\u00a0=\u00a06), 1,000\u00a0IU pregnant mare serum gonadotropin (PMSG group, <jats:italic>n<\/jats:italic>\u00a0=\u00a06), or 10\u00a0ml goat serum (control group, <jats:italic>n<\/jats:italic>\u00a0=\u00a06). Gilts in the AIS and PMSG groups were inseminated according to the FTAI protocol, and gilts in the control group were inseminated during natural oestrus. When PMSG was replaced by AIS during FTAI of gilts, ovulation rate and embryos recovered were significantly greater in the AIS group as compared to the other two groups (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05). Especially the average number of 6\u20138\u2010cell embryos in the AIS group was significantly higher than that in the PMSG group (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.01). Moreover, the blastocyst number in the AIS group was significantly higher than that in the PMSG group and the control group (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05). But there was no significant difference in the blastocyst number between the PMSG group and the control group (<jats:italic>p<\/jats:italic>\u00a0&gt;\u00a0.05). Besides, plasma levels of estradiol\u2010\u03b2 (E2) and progesterone (P4) were significantly greater in the AIS group as compared to the other two groups on Day 23 and D 27, respectively (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.01). In summary, we devised an improved high\u2010yield FTAI protocol for sexually mature gilts using AIS; this protocol had a greater superovulation efficiency than the FTAI using PMSG.<\/jats:p>","DOI":"10.1111\/rda.13854","type":"journal-article","created":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T18:21:11Z","timestamp":1604600471000},"page":"112-119","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Improving ovulation in gilts using anti\u2010inhibin serum treatment combined with fixed\u2010time artificial insemination"],"prefix":"10.1111","volume":"56","author":[{"given":"Ruoxin","family":"Jia","sequence":"first","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Science Zhejiang Academy of Agriculture Science  Hangzhou China"},{"name":"Department of Reproduction the Third of Affiliated Hospital of Xinxiang Medical University  Xinxiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Science Zhejiang Academy of Agriculture Science  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwei","family":"Zhu","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Science Zhejiang Academy of Agriculture Science  Hangzhou China"},{"name":"Ningbo Kuangdai Livestock Husbandry Technology Co. 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