{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T22:04:50Z","timestamp":1769724290935,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T00:00:00Z","timestamp":1618185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Contents<\/jats:title><jats:p>It is probable that reduced pregnancy rates in ewes after fixed time artificial insemination (FTAI) is attributable, in part, to the reduced number of normal spermatozoa that colonize the oviduct. Administration of oxytocin stimulates both cervical dilation and uterine\/oviductal contractility. The hypothesis that oxytocin can enhance sperm transport into the uteri and the oviducts, and thereby increase pregnancy rates, was tested in the present study. Oestrus was synchronized in 199 multiparous Kazak ewes using intravaginal flurogestone\u2010impregnated sponge. The sponge was left in the vagina for 12\u00a0days followed with an injection of 330\u00a0IU of eCG at sponge removal. Each ewe was intracervically inseminated twice at 50\u00a0hr and 62\u00a0hr after the removal of sponges using an insemination catheter containing 0.25\u00a0ml of diluted semen. Semen was collected from seven Texel rams and all the ejaculates were pooled and diluted in ultra\u2010high temperature\u2010treated commercial skimmed milk without (Control group, 0.05\u00a0ml of saline per mL milk, <jats:italic>n<\/jats:italic>\u00a0=\u00a0144) or with oxytocin supplement (Oxytocin group, 0.5\u00a0U of oxytocin per ml milk, <jats:italic>n<\/jats:italic>\u00a0=\u00a055). Pregnancy status was determined by transabdominal ultrasound examination 45\u00a0days after insemination. Lambing performance was recorded at delivery. Significant differences were observed between the Oxytocin group and the Control group in terms of the pregnancy rate and the fecundity rate (85.5% and 92.7% versus 68.8% and 72.9%, respectively). In conclusion, low dose oxytocin supplementation of semen extender significantly increased pregnancy and fecundity rates in oestrus\u2010synchronized Kazak ewes after FTAI.<\/jats:p>","DOI":"10.1111\/rda.13931","type":"journal-article","created":{"date-parts":[[2021,3,20]],"date-time":"2021-03-20T01:45:20Z","timestamp":1616204720000},"page":"942-947","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Oxytocin increases pregnancy rates after fixed time artificial insemination in Kazak ewes"],"prefix":"10.1111","volume":"56","author":[{"given":"Xiaoyu","family":"Lu","sequence":"first","affiliation":[{"name":"College of Animal Science and Technology Hebei Technology Innovation Center of Cattle and Sheep Embryo Hebei Agricultural University Baoding China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiyong","family":"Liu","sequence":"additional","affiliation":[{"name":"Institute of Xinjiang Yili Animal Science Yining China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Hebei Technology Innovation Center of Cattle and Sheep Embryo Hebei Agricultural University Baoding China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinglong","family":"Wu","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Hebei Technology Innovation Center of Cattle and Sheep Embryo Hebei Agricultural University Baoding China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7846-3561","authenticated-orcid":false,"given":"Xiangyun","family":"Li","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Hebei Technology Innovation Center of Cattle and Sheep Embryo Hebei Agricultural University Baoding China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.15653\/TPG-140341"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.1060055"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1365.046"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2017.07.021"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0531.2004.00534.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2014.01.003"},{"issue":"4","key":"e_1_2_10_8_1","first-page":"95","article-title":"The action of oxytocin on sperm motility. 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