{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:57:42Z","timestamp":1747187862845,"version":"3.40.5"},"reference-count":53,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T00:00:00Z","timestamp":1626393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017000","name":"Empresa de Pesquisa Agropecu\u00e1ria de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100017000","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study aimed to evaluate the correlation of seminal plasma IGF\u2010I and total proteins from peripubertal bulls with semen characteristics and onset of puberty. Sixteen dairy Gyr bulls were separated into early (<jats:italic>n<\/jats:italic>\u00a0=\u00a08) and regular (<jats:italic>n<\/jats:italic>\u00a0=\u00a08) groups, according to the onset of puberty. Semen was monthly collected by electroejaculation from 14 to 26\u00a0months of age, and the onset of puberty was retrospectively determined (17.0\u00a0\u00b1\u00a01.6 and 19.2\u00a0\u00b1\u00a01.5\u00a0months, to early and regular group, respectively). Five time points were evaluated (day \u221260, day \u221230, day 0, day 30 and day 60\u00a0days of puberty), being day 0 considered as beginning of puberty. Scrotal circumference and body weight were also assessed. Semen characteristics were evaluated, the seminal plasma was separated by centrifugation and total protein and IGF\u2010I concentrations were determined. There was no difference between groups to concentration of the seminal plasma total proteins, but we found an interaction between group and age. Seminal plasma IGF\u2010I concentrations were not different between early and regular groups; thus, the data were combined for analysis. Combined IGF\u2010I concentrations were positively correlated with sperm motility and concentration, age, body weight and scrotal circumference. Negative correlation was found between IGF\u2010I concentration and total sperm defects. Increased IGF\u2010I was observed in day \u221230 and day 0 of puberty in early and regular groups, respectively. Seminal plasma total proteins are involved in peripubertal modifications and IGF\u2010I from Zebus dairy bulls can influence the seminal characteristics and the growth factor increase occurs concomitantly with body growth but cannot be used to define puberty bulls earlier.<\/jats:p>","DOI":"10.1111\/rda.13987","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T07:28:25Z","timestamp":1625470105000},"page":"1279-1285","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Seminal plasma insulin\u2010like growth factor I and total protein concentration in peripubertal period of the Gyr bulls"],"prefix":"10.1111","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9474-9404","authenticated-orcid":false,"given":"Fernando Andrade","family":"Souza","sequence":"first","affiliation":[{"name":"Departamento de Medicina Veterin\u00e1ria Universidade Federal do Paran\u00e1 Paran\u00e1 Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0434-9221","authenticated-orcid":false,"given":"Jorge Andr\u00e9 Matias","family":"Martins","sequence":"additional","affiliation":[{"name":"Centro de Ci\u00eancias Agr\u00e1rias e da Biodiversidade Universidade Federal do Cariri Juazeiro do Norte Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1934-5183","authenticated-orcid":false,"given":"Lucas Luz","family":"Emerick","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural da Amaz\u00f4nia Parauapebas Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0888-769X","authenticated-orcid":false,"given":"Luciane Maria","family":"Laskoski","sequence":"additional","affiliation":[{"name":"Departamento de Medicina Veterin\u00e1ria Universidade Federal do Paran\u00e1 Paran\u00e1 Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4714-9406","authenticated-orcid":false,"given":"Jair","family":"Perez\u2010Osorio","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Agropecuarias Universidad de La Salle Bogot\u00e1 Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4721-1801","authenticated-orcid":false,"given":"Fabiana Ferreira","family":"de Souza","sequence":"additional","affiliation":[{"name":"Departamento de Cirurgia Veterin\u00e1ria e Reprodu\u00e7\u00e3o Animal FMVZ Universidade Estadual Paulista UNESP Botucatu Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5766-2748","authenticated-orcid":false,"given":"Astrid L.","family":"Paredes Ca\u00f1on","sequence":"additional","affiliation":[{"name":"Departamento de Salud Animal y Producci\u00f3n de Hato Universidad Nacional de Colombia Bogot\u00e1 Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4854-7625","authenticated-orcid":false,"given":"Vicente Ribeiro","family":"do Vale Filho","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais Escola de Veterin\u00e1ria da UFMG Belo Horizonte Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,7,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2017.08.016"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1006\/frne.2000.0197"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2527\/1998.7682032x"},{"key":"e_1_2_10_5_1","first-page":"1","article-title":"Molecular advances in semen quality assessment and improving fertility in bulls \u2010 a review","volume":"39","author":"Binsila B. K.","year":"2018","journal-title":"The Indian Journal of Animal Reproduction"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(76)90527-3"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP-06-0353"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2004.01.006"},{"volume-title":"Avalia\u00e7\u00e3o do modelo sigmoidal de Boltzmann na predi\u00e7\u00e3o do comportamento mec\u00e2nico de material biol\u00f3gico com propriedade viscoel\u00e1stica n\u00e3o linear (Evaluation of the Boltzmann sigmoidal model in predicting the mechanical behavior of biological material with non\u2010linear viscoelastic property)","year":"2007","author":"Burin E. L. K.","key":"e_1_2_10_9_1"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1210\/mend-3-7-1125"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2018.06.002"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD16122"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2014-8564"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(87)46024-2"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-09352006000500016"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.18.4.541"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod52.2.390"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod59.2.330"},{"volume-title":"Manual para exame androl\u00f3gico e avalia\u00e7\u00e3o do s\u00eamen animal (Guide for andrological examination and evaluation of the semen from animals)","year":"2013","author":"Henry M.","key":"e_1_2_10_19_1"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0739-7240(99)00023-5"},{"key":"e_1_2_10_21_1","first-page":"1146","volume-title":"Proceedings of the 12th Annual SAS Users Group International Conference","author":"Ipe D.","year":"1987"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.110.012583"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2018.11.032"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod49.6.1202"},{"issue":"101","key":"e_1_2_10_25_1","first-page":"2019","article-title":"Serum and seminal plasma IGF\u20101 associations with semen variables and effect of IGF\u20101 supplementation on semen freezing capacity in buffalo bulls","volume":"204","author":"Kumar P.","year":"2019","journal-title":"Animal Reproduction Science"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod67.2.648"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj3030121"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-09352011000600001"},{"volume-title":"Ra\u00e7as e tipos de cruzamentos para produ\u00e7\u00e3o de leite (Breeds and types of crosses for milk production)","year":"2009","author":"Miranda J. E. C.","key":"e_1_2_10_29_1"},{"key":"e_1_2_10_30_1","first-page":"3","article-title":"Seminal plasma proteins and fertility indexes in the bull: The case for osteopontin","volume":"2","author":"Moura A. A.","year":"2005","journal-title":"Animal Reproduction"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2006.03.012"},{"key":"e_1_2_10_32_1","first-page":"343","article-title":"IGF\u20101, IGF\u20101I and insulin promote differentiation of spermatogonia to primary spermatocytes in organ culture of newt testes","volume":"43","author":"Nakayama Y.","year":"1999","journal-title":"The International Journal of Developmental Biology"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2004.04.007"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.5713\/ajas.15.0586"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2017.04.049"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0093-691X(02)00662-3"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-015-2289-2"},{"key":"e_1_2_10_38_1","first-page":"1","article-title":"The use of insulin\u2010like growth factor 1 improved the parameters of the seminogram in a patient with severe oligoasthenoteratozoospermia","volume":"7","author":"Rodr\u00edguez J. A. M.","year":"2019","journal-title":"SAGE Open Medical Case Reports"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1051\/rnd:19890109"},{"volume-title":"User\u2019s Guide","year":"2002","author":"SAS","key":"e_1_2_10_40_1"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2008.08.011"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1201\/9780429244216"},{"key":"e_1_2_10_43_1","first-page":"21","article-title":"Biometria testicular, caracter\u00edsticas seminais, libido e concentra\u00e7\u00e3o de testosterona em ovinos da ra\u00e7a Santa In\u00eas, criados a campo, na microrregi\u00e3o de Campo Maior, Piau\u00ed (Testicular biometry, seminal characteristics, libido and testosterone concentration in Santa In\u00eas sheep, field\u2010bred in Campo Maior microregion, Piau\u00ed)","volume":"10","author":"Souza J. A. T.","year":"2007","journal-title":"Ci\u00eancia Veterin\u00e1ria Dos Tr\u00f3picos"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1159\/000182566"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.2741\/s450"},{"key":"e_1_2_10_46_1","first-page":"88","article-title":"The sperm journey in the excurrent duct: Functions of microvesicles on sperm maturation and gene expression along the epididymis","volume":"12","author":"Sullivan R.","year":"2015","journal-title":"Animal Reproduction"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0303-7207(02)00008-4"},{"key":"e_1_2_10_48_1","first-page":"363","volume-title":"Proceedings of VII Simp\u00f3sio de Produ\u00e7\u00e3o de Gado de Corte e III Simp\u00f3sio Internacional de Produ\u00e7\u00e3o de Gado","author":"Vale Filho V. R.","year":"2010"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-34152-w"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.103.022590"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2016-11866"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2016-12526"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas1965.243761x"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.domaniend.2018.03.008"}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.13987","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/rda.13987","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.13987","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T00:42:38Z","timestamp":1693356158000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.13987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,16]]},"references-count":53,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1111\/rda.13987"],"URL":"https:\/\/doi.org\/10.1111\/rda.13987","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"type":"print","value":"0936-6768"},{"type":"electronic","value":"1439-0531"}],"subject":[],"published":{"date-parts":[[2021,7,16]]},"assertion":[{"value":"2020-10-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}