{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T15:51:09Z","timestamp":1759938669504,"version":"3.40.5"},"reference-count":9,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T00:00:00Z","timestamp":1639008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Contents<\/jats:title><jats:p>This case study describes the effects of a contamination of boar bedding material with reprotoxic compounds in an AI centre in southern Germany. The origin of the investigations was an extreme decline in the production output of the boars. In July 2021, more than 54% of boars were not in production and over 45% of ejaculates had insufficient sperm quality and quantity, which is a significant drop in comparison with the other months. This drop was accompanied by oligozoospermia (azoospermia), asthenozoospermia and teratozoospermia. Through intensive troubleshooting, the changes could be attributed to fenpropimorph, an ergosterol biosynthesis\u2010inhibiting fungicide with reprotoxic potential, which was found in the sawdust used as bedding as well as in liver samples of affected animals, reaching a concentration (mean\u00a0\u00b1\u00a0<jats:italic>SD<\/jats:italic>) between 0.20\u00a0\u00b1\u00a00.36\u00a0mg\/kg and 0.019\u00a0\u00b1\u00a00.001\u00a0mg\/kg respectively. Furthermore, autopsy findings revealed hyperaemia of the testis, histologically focal degeneration of the germinal epithelium and signs of reduced spermatogenesis and spermiogenesis.<\/jats:p>","DOI":"10.1111\/rda.14062","type":"journal-article","created":{"date-parts":[[2021,12,4]],"date-time":"2021-12-04T14:30:26Z","timestamp":1638628226000},"page":"337-340","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Reprotoxic effects of fenpropimorph on the fertilizing potential of AI boars: A case study"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7932-9412","authenticated-orcid":false,"given":"Martin","family":"Schulze","sequence":"first","affiliation":[{"name":"Institute for Reproduction of Farm Animals Sch\u00f6now Bernau Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Britta","family":"Hensel","sequence":"additional","affiliation":[{"name":"Institute for Reproduction of Farm Animals Sch\u00f6now Bernau Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8296-5620","authenticated-orcid":false,"given":"David","family":"Schr\u00f6ter","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Getreideverarbeitung GmbH Nuthetal Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claus","family":"Leiding","sequence":"additional","affiliation":[{"name":"Besamungsverein Neustadt a. d. Aisch e. V. Neustadt a. d. Aisch Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Jung","sequence":"additional","affiliation":[{"name":"Institute for Reproduction of Farm Animals Sch\u00f6now Bernau Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Lautner","sequence":"additional","affiliation":[{"name":"Besamungsverein Neustadt a. d. Aisch e. V. Neustadt a. d. Aisch Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.106.053835"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2008.07.011"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2013.3359"},{"volume-title":"Study of the toxicity of Reg. No. 108 406 to dogs in a 4\u2010week feeding study","year":"1978","author":"Kirsch P.","key":"e_1_2_8_5_1"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2004.09.039"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2014.09.001"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0701079"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2019.05.042"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20100004.2005.00515.x"}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.14062","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/rda.14062","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.14062","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T00:49:50Z","timestamp":1692838190000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.14062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,9]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1111\/rda.14062"],"URL":"https:\/\/doi.org\/10.1111\/rda.14062","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"type":"print","value":"0936-6768"},{"type":"electronic","value":"1439-0531"}],"subject":[],"published":{"date-parts":[[2021,12,9]]},"assertion":[{"value":"2021-09-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}