{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T15:36:30Z","timestamp":1768404990843,"version":"3.49.0"},"reference-count":40,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,4,25]],"date-time":"2022-04-25T00:00:00Z","timestamp":1650844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Sustainability of dairy production depends largely on reproductive efficiency that is affected by heat stress due to high ambient temperature and humidity during summer. Supplementation of minerals has been proposed as a management strategy to minimize adverse impact of heat stress on fertility. The objective of this study was to determine the effects of an injectable mineral supplement (Fosfosan) containing selenium (Se), copper (Cu), potassium (K), magnesium (Mg) and phosphorus (P) on the ovarian structures, reproductive hormones and conception rate of heat\u2010stressed Holstein cows. Sixteen cows were assigned during summer to one of two treatments, a control group (CON; <jats:italic>n<\/jats:italic>\u00a0=\u00a08) and a mineral\u2010supplemented group (SUP; <jats:italic>n<\/jats:italic>\u00a0=\u00a08). Ambient temperature and relative humidity records were collected and processed to estimate the temperature\u2013humidity index (THI), which confirmed a heat\u2010stressed environment during the study (avg. THI\u00a0=\u00a079.4). Cows were subjected to a fixed\u2010time artificial insemination (FTAI) program using the CIDR\u2010Synch synchronization protocol. Traits indicative of ovarian activity were recorded during and after this protocol, as well as serum concentrations of reproductive hormones. Pregnancy diagnosis was made 28 and 35 d after FTAI. A completely randomized block design with repeated measures over time was performed to study ovarian functional structures and its hormonal profiles. Correlations and regressions were estimated to study relationships between ovarian structures and related hormones. Mineral supplementation did not increase follicular diameter or follicular populations (<jats:italic>p<\/jats:italic>\u00a0&gt;\u00a0.05), yet tended to increase corpus luteum diameter (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.10), and it enhanced (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.01) oestrogen and progesterone serum concentrations and improved (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05) cow's conception rate. Diameter of dominant follicles and corpus luteum was correlated (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05) with oestrogen and progesterone levels, respectively, but only in mineral\u2010treated cows. Two additional dairy herds were evaluated to confirm that mineral supplementation improved conception rate during the heat stress period (objective 2). Cows from dairy 1 received FTAI during winter (<jats:italic>n<\/jats:italic>\u00a0=\u00a0401) and summer (<jats:italic>n<\/jats:italic>\u00a0=\u00a0240), whereas cows from dairy 2 were bred after natural detected oestrus during winter (<jats:italic>n<\/jats:italic>\u00a0=\u00a0558) and summer (<jats:italic>n<\/jats:italic>\u00a0=\u00a0314). Conception rates were higher (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05) in winter than summer and they improved (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05) with mineral supplementation, but only in cows managed during summer. In conclusion, supplementation of minerals enhanced hormonal secretion from ovarian structures and improved conception rate in Holstein cows exposed to summer heat stress.<\/jats:p>","DOI":"10.1111\/rda.14125","type":"journal-article","created":{"date-parts":[[2022,4,18]],"date-time":"2022-04-18T06:55:02Z","timestamp":1650264902000},"page":"839-848","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Mineral supplementation (injectable) improved reproductive performance in Holstein cows managed in a warm summer environment"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4880-641X","authenticated-orcid":false,"given":"Andrea D.","family":"Del R\u00edo\u2010Avil\u00e9s","sequence":"first","affiliation":[{"name":"Instituto de Ciencias Agr\u00edcolas Universidad Aut\u00f3noma de Baja California  Mexicali Baja California M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abelardo","family":"Correa\u2010Calder\u00f3n","sequence":"additional","affiliation":[{"name":"Instituto de Ciencias Agr\u00edcolas Universidad Aut\u00f3noma de Baja California  Mexicali Baja California M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonel","family":"Avenda\u00f1o\u2010Reyes","sequence":"additional","affiliation":[{"name":"Instituto de Ciencias Agr\u00edcolas Universidad Aut\u00f3noma de Baja California  Mexicali Baja California M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6947-2247","authenticated-orcid":false,"given":"Ulises","family":"Mac\u00edas\u2010Cruz","sequence":"additional","affiliation":[{"name":"Instituto de Ciencias Agr\u00edcolas Universidad Aut\u00f3noma de Baja California  Mexicali Baja California M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milton G.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences Colorado State University  Fort Collins Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. 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