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In addition, prevention of unintended reproduction especially in feral horse populations may require methods for suppression of gonadal function. Surgical ovariectomy is a safe method but not an acceptable approach in feral mares and undesired in mares where future breeding is considered. There are different approaches for artificial prolongation of the luteal phase resulting in transient inhibition of oestrus and ovulation. Among those, treatment with natural or synthetic progestogens is considered the most common and successful method. Whereas application of intrauterine devices may result in prolongation of luteal function in non\u2010pregnant mares, intrauterine insertion of glass balls is no longer recommended because of complications in individual mares. There are several safer alternatives that may be of interest, especially for population control in free\u2010roaming horses. Treatment with long\u2010acting deslorelin implants inhibited ovulation and oestrus behaviour in mares for limited and variable time intervals in a dose\u2010dependent manner. The effect of GnRH vaccines varies considerably among individual mares, is age dependent, and oestrus\u2010like behaviour may still occur. Contraception via immunization against native porcine or recombinant zona pellucida antigen is successful, but immunocontraception is as much a result of ovarian inactivity as an antibody\u2010based block to sperm\u2010oocyte binding. In conclusion, several treatments for suppression of gonadal function in mares are available, but there are advantages and disadvantages associated that have to be considered. The treatment of choice will thus differ with regard to the demands.<\/jats:p>","DOI":"10.1111\/rda.14129","type":"journal-article","created":{"date-parts":[[2022,4,25]],"date-time":"2022-04-25T08:14:53Z","timestamp":1650874493000},"page":"4-12","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Suppression of reproductive behaviour and gonadal function in female horses\u2014An update"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6077-7362","authenticated-orcid":false,"given":"Christine","family":"Aurich","sequence":"first","affiliation":[{"name":"Artificial Insemination and Embryo Transfer Department for Small Animals and Horses Vetmeduni Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martim","family":"Kaps","sequence":"additional","affiliation":[{"name":"Artificial Insemination and Embryo Transfer Department for Small Animals and Horses Vetmeduni Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042\u20103306.1973.tb03213.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2009.07.013"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0018\u2010506X(80)90014\u20108"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0739(17)30704-6"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1470195"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165\u20100378(99)00063\u20107"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168\u20101656(99)00112\u20101"},{"key":"e_1_2_7_9_1","volume-title":"BHA NOTICE \u2013 REGUMATE EQUINE","author":"British Horserace Authority","year":"2018"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.21836\/PEM20080122"},{"key":"e_1_2_7_11_1","first-page":"1451","article-title":"Colic\u2010like discomfort associated with ovulation in two mares","volume":"191","author":"Cox J. 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