{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T07:47:18Z","timestamp":1775980038410,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To evaluate the effect of oxytocin as a cervical dilator, a study was carried out on nulliparous goats inseminated transcervically at the beginning of the breeding season. One hundred sixteen nulliparous goats with a mean live weight of 33.4\u00a0\u00b1\u00a00.68\u00a0kg and an age of 13.7\u00a0\u00b1\u00a00.37\u00a0months were used. The goats were exposed to active bucks of proven fertility for a period of 14 d in order to induce oestrus. One week later, the Ovsynch protocol was applied, which consisted of the application of 20\u00a0mg of gonadorelin (Day Zero), 0.075\u00a0mg of cloprostenol (Day 7) and of a second dose of 20\u00a0mg of gonadorelin applied on Day 9. Artificial insemination (AI) was performed 16\u00a0hr later. Three treatments were evaluated: T1\u00a0=\u00a050\u00a0IU saline, T2\u00a0=\u00a025\u00a0IU oxytocin; T3\u00a0=\u00a050\u00a0IU of oxytocin, intravenously applied 10\u201315\u00a0min before AI. The time required to inseminate each treated goat from groups T2 and T3 was 49.56 and 56.25\u00a0s, respectively, versus 85.78\u00a0s needed for the goats from group T1 (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.0001). In the T1 group of goats, the insemination catheter was inserted 2.1\u00a0cm into the cervical canal and in goats from groups T2 and T3 it reached 3.41 and 3.77\u00a0cm into the cervical canal, respectively (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.02). Pregnancy rates and prolificacy (kids\/doe) were higher (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.02) for groups T2 (82.93%; 1.16) and T3 (76.92%; 1.21) respectively than for control goats (61.11%; 0.69). In conclusion, the intravenous administration of oxytocin led to greater dilation and depth of cervical penetration, obtaining higher pregnancy rates and prolificacy.<\/jats:p>","DOI":"10.1111\/rda.14135","type":"journal-article","created":{"date-parts":[[2022,4,25]],"date-time":"2022-04-25T12:34:35Z","timestamp":1650890075000},"page":"886-892","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The use of oxytocin to cause cervical dilation for transcervical insemination in nulliparous goats: Improving pregnancy and kidding rates"],"prefix":"10.1111","volume":"57","author":[{"given":"Valeria Alvarado","family":"Gutierrez","sequence":"first","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia Posgrado Conjunto FA\u2010FMVZ Universidad Aut\u00f3noma de Nuevo Le\u00f3n  General Escobedo M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1576-6845","authenticated-orcid":false,"given":"Fernando","family":"S\u00e1nchez\u2010D\u00e1vila","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia Posgrado Conjunto FA\u2010FMVZ Universidad Aut\u00f3noma de Nuevo Le\u00f3n  General Escobedo M\u00e9xico"},{"name":"Laboratorio de Reproducci\u00f3n Animal Unidad Acad\u00e9mica Mar\u00edn  Mar\u00edn M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rogelio Alejandro","family":"Ledezma\u2010Torres","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia Posgrado Conjunto FA\u2010FMVZ Universidad Aut\u00f3noma de Nuevo Le\u00f3n  General Escobedo M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam","family":"Peterson","sequence":"additional","affiliation":[{"name":"School of Agriculture and Environment Massey University  Palmerston North New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Estela Garza","family":"Brenner","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia Posgrado Conjunto FA\u2010FMVZ Universidad Aut\u00f3noma de Nuevo Le\u00f3n  General Escobedo M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Luna\u2010Palomera","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n de Ciencias Agropecuarias 86280 Universidad Aut\u00f3noma de Ju\u00e1rez de Tabasco  Villahermosa M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Fernando","family":"Vazquez\u2010Armijo","sequence":"additional","affiliation":[{"name":"Universidad Aut\u00f3noma del Estado de M\u00e9xico Centro Universitario Temascaltepec  Temascaltepec M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicol\u00e1s","family":"L\u00f3pez\u2010Villalobos","sequence":"additional","affiliation":[{"name":"School of Agriculture and Environment Massey University  Palmerston North New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juraj","family":"Grizelj","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria Universidad de Zagreb  Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,5]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"174","article-title":"Age related morphological changes in the cervix of the West African dwarf goat (Capra hircus)","volume":"11","author":"Abiaezute C. 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